ArticleClinical and experimental reproductive medicine2017
ICSI significantly improved the pregnancy rate of patients with a high sperm DNA fragmentation index.
Article in Clinical and experimental reproductive medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-correlation of Sperm Morphology and DNA Fragmentation Index.Reproductive sciences (Thousand Oaks, Calif.) · 2025Pooled it
- Review
- The association of spermInternational journal of reproductive biomedicine · 2024Article
- Sperm deoxyribonucleic acid fragmentation: predictors, fertility outcomes, and assays among infertile males.F&S reports · 2021Article
- Sperm morphology and DNA fragmentation after zona pellucida selection.Reproduction & fertility · 2021Article
- Sperm selection during ICSI treatments reduces single- but not double-strand DNA break values compared to the semen sample.Journal of assisted reproduction and genetics · 2021Article
- High mRNA expression of GABA receptors in human sperm with oligoasthenoteratozoospermia and teratozoospermia and its association with sperm parameters and intracytoplasmic sperm injection outcomes.Clinical and experimental reproductive medicine · 2021Article
- Predictive Significance of Sperm DNA Fragmentation Testing in Early Pregnancy Loss in Infertile Couples Undergoing Intracytoplasmic Sperm Injection.Research and reports in urology · 2021Article
- Thoughts on the popularity of ICSI.Journal of assisted reproduction and genetics · 2021Review
- Progress in Research on Sperm DNA Fragmentation.Medical science monitor : international medical journal of experimental and clinical research · 2020Review
- Article
- Early fragment removal onClinical and experimental reproductive medicine · 2018Article
- Efficacy of Various Sperm Selection Strategies in Obtaining Sperm with Improved DNA Integrity: A Prospective Study.American journal of men's healthArticle
- The Effect of Sperm DNA Fragmentation Index on the Outcome of Intrauterine Insemination and Intracytoplasmic Sperm Injection.Journal of human reproductive sciencesArticle
- Random sperm DNA fragmentation index is not associated with clinical outcomes in day-3 frozen embryo transfer.Asian journal of andrologyArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCorrelations between semen parameters and sperm DNA fragmentation index (DFI) were investigated to identify characteristics of sperm without DNA damage that could be used in selecting sperm for intracytoplasmic sperm injection (ICSI). Pregnancy outcomes were compared to determine whether
methodsSemen analysis was carried out in 388 patients who visited our IVF center for the first time to investigate correlations between sperm DFI and semen parameters. In addition, 1,102 IVF cycles in 867 patients were carried out in the present study; 921 cycles in the low-DFI group (DFI <30%) and 181 cycles in the high-DFI group (DFI ≥30%). Both the low- and high-DFI groups were subdivided into IVF and ICSI cycle groups.
resultsSperm DFI showed significant inverse correlations with sperm motility (
conclusionICSI is a better choice than IVF for improving the pregnancy outcomes of patients who have sperm with a high DFI.
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