Evidence map›Paper›PMID 29026689›Full record

ReviewWorld journal of methodology2017

Accurate diagnosis of prenatal cleft lip/palate by understanding the embryology.

Bram Smarius, Charlotte Loozen, Wendy Manten, Mireille Bekker, Lou Pistorius, Corstiaan Breugem

Registry-linked trialAbstract readReview
In one paragraph

Review in World journal of methodology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06523855 (Clinical and Radiographic Evaluation of Bilateral Alveolar Cleft Grafting With Micro Plate Stabilization Versus Conventional Grafting Technique), which is not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06523855 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Clinical and Radiographic Evaluation of Bilateral Alveolar Cleft Grafting With Micro Plate Stabilization Versus Conventional Grafting Technique: A Preliminary Clinical Trial

TypeinterventionalSponsorCairo UniversityRan2024 to 2025Enrolled12ConditionsAlveolar CleftArmsbilateral alveolar cleft grafting using iliac crest particulate and microplate fixation
3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Feasibility of Imaging the Uvula at the Midtrimester Anomaly Ultrasound: A Retrospective Study.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Analysis of MSX1, RYK, NFκB p65, and CCL4 Proteins andInternational journal of molecular sciences · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Damaging Mutations inThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2024
    Article
  18. Observational
  19. Article
  20. Updates in Cleft Care.Seminars in plastic surgery · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bram SmariusDivision of Pediatric Plastic Surgery, Cleft Palate Team, Wilhelmina Children's Hospital, 3584 EA Utrecht, The Netherlands. b.j.a.smarius@umcutrecht.nl.
Charlotte LoozenDivision of Pediatric Plastic Surgery, Cleft Palate Team, Wilhelmina Children's Hospital, 3584 EA Utrecht, The Netherlands.
Wendy MantenDivision of Gynecology and Obstetrics, Wilhelmina Children's Hospital, 3584 EA Utrecht, The Netherlands.
Mireille BekkerDivision of Gynecology and Obstetrics, Wilhelmina Children's Hospital, 3584 EA Utrecht, The Netherlands.
Lou PistoriusDivision of Gynecology and Obstetrics, Stellenbosch University and Tygerberg Hospital, Cape Town 7500, South Africa.
Corstiaan BreugemDivision of Pediatric Plastic Surgery, Cleft Palate Team, Wilhelmina Children's Hospital, 3584 EA Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cleft lip with or without cleft palate (CP) is one of the most common congenital malformations. Ultrasonographers involved in the routine 20-wk ultrasound screening could encounter these malformations. The face and palate develop in a very characteristic way. For ultrasonographers involved in screening these patients it is crucial to have a thorough understanding of the embryology of the face. This could help them to make a more accurate diagnosis and save time during the ultrasound. Subsequently, the current postnatal classification will be discussed to facilitate the communication with the CP teams.

Indexed as

Cleft lipCleft palateEmbryology faceOrofacial cleftsUltrasound

Identifiers

PMID29026689
PMCPMC5618146

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.