Evidence map›Paper›PMID 29026663›Full record

ArticleSurgical neurology international2017

Ependymal enhancement on magnetic resonance imaging for the identification of high-grade gliomas.

Muhammad Waqas, Muzna Iftikhar, Usman T Siddiqui, Syed Ather Enam

Abstract read
In one paragraph

Article in Surgical neurology international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhammad WaqasDepartment of Surgery, Section of Neurosurgery, The Aga Khan University Hospital, Karachi, Pakistan.
Muzna IftikharDepartment of Surgery, Section of Neurosurgery, The Aga Khan University Hospital, Karachi, Pakistan.
Usman T SiddiquiDepartment of Surgery, Section of Neurosurgery, The Aga Khan University Hospital, Karachi, Pakistan.
Syed Ather EnamDepartment of Surgery, Section of Neurosurgery, The Aga Khan University Hospital, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-grade gliomas have high infiltrative potential and spread along white matter and blood vessels. Enhancement of ependymal lining on magnetic resonance imaging (MRI) is considered as a marker of parenchymal spread of disease. In this study, we aimed to assess the sensitivity, specificity, and positive and negative predictive values of ependymal enhancement (EE) for identification of high-grade glial tumors.

methodsWe reviewed preoperative MRI scans of 94 consecutive patients surgically treated for space occupying lesions of the brain for EE. Assessment for EE was blind to the final histopathological diagnosis of the patient. An enhancement of more than 2 mm was considered positive. Pathologies of these patients were reviewed and matched to the radiological findings. Percentage and proportion of EE in glial and non-glial pathology groups was then calculated and a sensitivity and specificity analysis was performed.

resultsThe population included 94 cases (64 males and 30 females) with population mean age 45 ± 15.5 years. Sensitivity of EE in differentiating glioma from total number of cases was 82.61% specificity 35.42% (

conclusionEE has moderate sensitivity and specificity for high-grade gliomas. However, larger sample studies are required for further validation of this observations.

Indexed as

Ependymal enhancementhigh-grade gliomatumor spread

Identifiers

PMID29026663
PMCPMC5629847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.