ReviewUnited European gastroenterology journal2017
Effect of prophylactic clipping in colorectal endoscopic resection: A meta-analysis of randomized controlled studies.
Review in United European gastroenterology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Pooled it
- Effect of prophylactic clip placement following endoscopic mucosal resection of large colorectal lesions on delayed polypectomy bleeding: A meta-analysis.World journal of gastroenterology · 2019Pooled it
- Clinical Trial: Precise Administration of Sucralfate Powder in Prevention of Delayed Postpolypectomy Bleeding. A Randomized Controlled Trial.Clinical and translational gastroenterology · 2025Trial
- Safety Profile of Low-Power Pure-Cut Hot Snare Polypectomy for 10-14 mm Nonpedunculated Colorectal Neoplasms.DEN open · 2026Article
- Dual Channel Endoscopic Mucosal Resection.Clinics in colon and rectal surgery · 2024Review
- Systematic review of self-assembling peptides as topical agents for treatment and prevention of gastrointestinal bleeding.Clinical endoscopy · 2024Article
- Unlocking quality in endoscopic mucosal resection.World journal of gastrointestinal endoscopy · 2023Review
- Efficacy of self-assembling peptide in mitigating delayed bleeding after advanced endoscopic resection of gastrointestinal lesions: A meta-analysis.Endoscopy international open · 2023Article
- Clip-assisted endoloop ligation of the mucosal defect after resection of colorectal polyps decreased postprocedural delayed bleeding.Therapeutic advances in gastroenterology · 2022Article
- The Use of Endoscopic Clipping in Preventing Delayed Complications after Endoscopic Resection for Superficial Non-Ampullary Duodenal Tumors.Clinical endoscopy · 2021Article
- Prevention and Management of Complications and Education in Endoscopic Submucosal Dissection.Journal of clinical medicine · 2021Review
- Additional Mosapride to Proton Pump Inhibitor for Gastroesophageal Reflux Disease: A Meta-Analysis.Journal of clinical medicine · 2020Article
- EMR/ESD: Techniques, Complications, and Evidence.Current gastroenterology reports · 2020Review
- Endoscopic Management of Post-Polypectomy Bleeding.Clinical endoscopy · 2020Review
- Prophylactic Endoscopic Clipping Does Not Prevent Delayed Postpolypectomy Bleeding in Routine Clinical Practice: A Propensity Score-Matched Cohort Study.The American journal of gastroenterology · 2020Article
- Use of the Endoscopic Clipping Over the Scope Technique to Treat Acute Severe Lower Gastrointestinal Bleeding in the Colon and Anal Transition Zone.Gastrointestinal endoscopy clinics of North America · 2020Review
- Complete closure versus simple closure for perforations during colorectal endoscopic submucosal dissection.Endoscopy international open · 2020Article
- Effects of Encircled Abdominal Compression Device in Colonoscopy: A Meta-Analysis.Journal of clinical medicine · 2019Review
- Routine Prophylactic Endoscopic Clipping Is Not Efficacious in the Prevention of Delayed Post-Polypectomy Bleeding: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of the Canadian Association of Gastroenterology · 2019Article
- Haemostasis and prevention of bleeding related to ER: The role of a novel self-assembling peptide.United European gastroenterology journal · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimThe efficacy of clipping for preventing delayed bleeding after colorectal endoscopic resection is still controversial. To assess the efficacy of prophylactic clipping, we conducted a meta-analysis of randomized controlled trials.
methodsWe searched PubMed, the Cochrane library, and the Igaku-chuo-zasshi database for randomized trials eligible for inclusion in our meta-analysis. We identified seven eligible randomized trials from the database search, and compared the effect of clipping versus non-clipping with respect to delayed bleeding and perforation. Data from eligible studies were combined to calculate pooled odds ratios (ORs).
resultsPostoperative bleeding was observed in 41 of 1526 cases (2.7%) without clipping and in 32 of 1533 cases (2.1%) with clipping (OR 0.76, 95% CI: 0.39-1.47,
conclusionsProphylactic clipping did not decrease the occurrence of delayed bleeding after colorectal endoscopic resection. Clipping could be of interest in patients with a high risk of bleeding (anticoagulation) or large lesions, but with the available trials data to prove this are scarce.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.