Evidence map›Paper›PMID 29026443›Full record

ArticleDiabetology & metabolic syndrome2017

Neutrophil killing of

Ingrid Lea Scully, Lisa Kristin McNeil, Sudam Pathirana, Christine Lee Singer, Yongdong Liu, Stanley Mullen, Douglas Girgenti, Alejandra Gurtman, Michael W Pride, Kathrin Ute Jansen and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Diabetology & metabolic syndrome, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. The Antimicrobial Activity ofMolecules (Basel, Switzerland) · 2021
    Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Diet-induced obesity in mice impairs host defense againstAmerican journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Ingrid Lea ScullyPfizer Vaccine Research and Development, 401 North Middletown Rd, Pearl River, NY 10965 USA.
Lisa Kristin McNeilPfizer Vaccine Research and Development, 401 North Middletown Rd, Pearl River, NY 10965 USA.
Sudam PathiranaPfizer Vaccine Research and Development, 401 North Middletown Rd, Pearl River, NY 10965 USA.
Christine Lee SingerPfizer Vaccine Research and Development, 401 North Middletown Rd, Pearl River, NY 10965 USA.
Yongdong LiuPfizer Vaccine Research and Development, 401 North Middletown Rd, Pearl River, NY 10965 USA.
Stanley MullenPfizer Vaccine Research and Development, 401 North Middletown Rd, Pearl River, NY 10965 USA.
Douglas GirgentiPfizer Vaccine Research and Development, 401 North Middletown Rd, Pearl River, NY 10965 USA.
Alejandra GurtmanPfizer Vaccine Research and Development, 401 North Middletown Rd, Pearl River, NY 10965 USA.
Michael W PridePfizer Vaccine Research and Development, 401 North Middletown Rd, Pearl River, NY 10965 USA.
Kathrin Ute JansenPfizer Vaccine Research and Development, 401 North Middletown Rd, Pearl River, NY 10965 USA.
Paul L HuangCardiovascular Research Center and Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA USA.
Annaliesa S AndersonPfizer Vaccine Research and Development, 401 North Middletown Rd, Pearl River, NY 10965 USA.
Pfizer (United States) · USMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity, metabolic syndrome (MetS), and diabetes are frequent in surgical populations and can enhance susceptibility to postoperative surgical site infections. Reduced neutrophil function has been linked with diabetes and risk of

methodsNeutrophil function (chemotaxis, phagocytosis, and opsonophagocytic killing of

resultsNeutrophil function was similar for comorbid and healthy cohorts, with no significant between-group differences in cell counts, migration, phagocytosis ability, neutrophil subset proportions, and

conclusionsMetS, diabetes, and obesity do not impact in vitro neutrophil function with regard to

Indexed as

DiabetesImmune functionMetabolic syndromeNeutrophilsObesityStaphylococcus aureusVaccine

Identifiers

PMID29026443
PMCPMC5627489
OpenAlexW2762762130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.