Evidence map›Paper›PMID 29026434›Full record

ArticlePlant methods2017

A plant-based chemical genomics screen for the identification of flowering inducers.

Martijn Fiers, Jorin Hoogenboom, Alice Brunazzi, Tom Wennekes, Gerco C Angenent, Richard G H Immink

Open access · goldAbstract read
In one paragraph

Article in Plant methods, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Comparative genomics of flowering behavior inFrontiers in plant science · 2023
    Article
  6. Article
  7. Flowering plants return to the sea….Journal of experimental botany · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Martijn FiersBioscience, Wageningen University and Research, 6700 AP Wageningen, The Netherlands.
Jorin HoogenboomLaboratory of Organic Chemistry, Wageningen University and Research, 6708 WE Wageningen, The Netherlands.
Alice BrunazziBioscience, Wageningen University and Research, 6700 AP Wageningen, The Netherlands.
Tom WennekesLaboratory of Organic Chemistry, Wageningen University and Research, 6708 WE Wageningen, The Netherlands.
Gerco C AngenentBioscience, Wageningen University and Research, 6700 AP Wageningen, The Netherlands.
Richard G H ImminkBioscience, Wageningen University and Research, 6700 AP Wageningen, The Netherlands.
Wageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFloral timing is a carefully regulated process, in which the plant determines the optimal moment to switch from the vegetative to reproductive phase. While there are numerous genes known that control flowering time, little information is available on chemical compounds that are able to influence this process. We aimed to discover novel compounds that are able to induce flowering in the model plant Arabidopsis. For this purpose we developed a plant-based screening platform that can be used in a chemical genomics study.

resultsHere we describe the set-up of the screening platform and various issues and pitfalls that need to be addressed in order to perform a chemical genomics screening on Arabidopsis plantlets. We describe the choice for a molecular marker, in combination with a sensitive reporter that's active in plants and is sufficiently sensitive for detection. In this particular screen, the firefly Luciferase marker was used, fused to the regulatory sequences of the floral meristem identity gene

conclusionsIn this study a chemical genomics screening platform was developed to discover compounds that can induce flowering in Arabidopsis. This platform was used successfully, to identify a compound that can speed-up flowering in Arabidopsis.

Indexed as

APETALA1ArabidopsisChemical genomicsFloweringLuciferaseSalicylic acid

Identifiers

PMID29026434
PMCPMC5627458
OpenAlexW2761339663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.