Evidence map›Paper›PMID 29026425›Full record

ReviewJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2017

Effect of cytochrome P450 2C19*17 allelic variant on cardiovascular and cerebrovascular outcomes in clopidogrel-treated patients: A systematic review and meta-analysis.

Bo Huang, De-Jun Cui, Ying Ren, Bin Han, Da-Ping Yang, Xun Zhao

Open access · goldAbstract readReview
In one paragraph

Review in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Prevalence ofPharmacogenomics and personalized medicine · 2025
    Article
  4. The Diversity ofThe application of clinical genetics · 2024
    Article
  5. Article
  6. Article
  7. ThePharmacogenomics and personalized medicine · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bo HuangDepartment of Gastroenterology, The Affiliated People's Hospital of Guizhou Medical University, Guizhou Province, PR China.
De-Jun CuiDepartment of Gastroenterology, The Affiliated People's Hospital of Guizhou Medical University, Guizhou Province, PR China.
Ying RenDepartment of Internal Medicine, Guizhou Provincial Traffic Hospital, Guizhou Province, PR China.
Bin HanDepartment of Gastroenterology, The Affiliated People's Hospital of Guizhou Medical University, Guizhou Province, PR China.
Da-Ping YangDepartment of Gastroenterology, The Affiliated People's Hospital of Guizhou Medical University, Guizhou Province, PR China.
Xun ZhaoDepartment of Gastroenterology, The Affiliated People's Hospital of Guizhou Medical University, Guizhou Province, PR China.
Guiyang Medical University · CNGuizhou Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to evaluate the associations of gain-of-function allele of MATERIALS AND

methodsLiterature search was conducted in PubMed, EMBASE, and Cochrane Library. Odds ratio (OR) combined with 95% confidence interval (CI) was the pooled statistics. Subgroup analysis was performed by disease type, bleeding events, and race.

resultsThirteen eligible studies involving 14,239 patients with

conclusion

Indexed as

Bleedingcardiovascular and cerebrovascular diseaseclopidogrelCYP2C19*17high platelet reactivitymajor adverse cardiovascular and cerebrovascular eventsmeta-analysis

Identifiers

PMID29026425
PMCPMC5629834
OpenAlexW2757833509

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.