Evidence map›Paper›PMID 29026395›Full record

ArticleAfrican health sciences2017

Tuberculosis among HIV-infected population: incidence and risk factors in rural Tanzania.

K Said, S Verver, A Kalingonji, F Lwilla, A Mkopi, S Charalambous, K Reither

Open access · diamondAbstract read
In one paragraph

Article in African health sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

K SaidIfakara Health Institute, Bagamoyo Research and Training Centre, P O Box 74, Tanzania.
S VerverKNCV Tuberculosis Foundation, and Amsterdam Institute of Global Health and Development, Academic Medical Centre Amsterdam, The Netherlands.
A KalingonjiDistrict AIDS Coordinator, CTC, Bagamoyo District Hospital, Bagamoyo, Tanzania.
F LwillaIfakara Health Institute, Bagamoyo Research and Training Centre, P O Box 74, Tanzania.
A MkopiIfakara Health Institute, Bagamoyo Research and Training Centre, P O Box 74, Tanzania.
S CharalambousAurum Institute, 29 Queens Road, Johannesburg, 2194, South Africa.
K ReitherIfakara Health Institute, Bagamoyo Research and Training Centre, P O Box 74, Tanzania.
Swiss Tropical and Public Health Institute · CHErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of tuberculosis among HIV-infected populations with high CD4 count in high burden countries has not been well studied.

objectiveTo assess the TB incidence in HIV-infected adults and its associated risk factors.

methodA cohort study with retrospective review of medical records and prospective follow-up of HIV-infected adult participants attending CTC who were 18-55 years old, had CD4 count more than 250 cells/mm

resultsOverall 777 (24%) of 3,279 CTC enrolled HIV-infected adults fulfilled the inclusion criteria of the study. The incidence of TB in the study population ranged from 0.8/100 per person years (PY) at risk (95% CI 0.5-1.3) in the main analysis to 1.7/100 PY at risk (95% CI 1.0-2.6) in sensitivity analyses. Only prior history of TB disease was found to have a significant association with an increased risk of TB, hazard ratio 5.7 (95% CI 2.0-16.4, p value 0.001).

conclusionTuberculosis incidence among HIV-infected adults with medium/high CD4 count in Bagamoyo is lower than in other high TB burden countries. Previously TB treated patients have a much higher risk of getting TB again than those who never had TB before.

Indexed as

Antiretroviral Therapy, Highly ActiveAdolescentAdultAnti-HIV AgentsCD4 Lymphocyte CountCoinfectionHIV InfectionsHospitals, DistrictHumansIncidenceMiddle AgedProportional Hazards ModelsRisk FactorsRural PopulationTanzaniaTuberculosisAnti-HIV AgentsCare and Treatment CenterCD4 cell countHIVTuberculosis

Identifiers

PMID29026395
PMCPMC5636250
OpenAlexW2619891079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.