Evidence map›Paper›PMID 29026382›Full record

ArticleAfrican health sciences2017

Role of plasma adiponectin /C-reactive protein ratio in obesity and type 2 diabetes among African Americans.

Preetha Anna Abraham, Selasi Attipoe, Josh B Kazman, Stacey Anne Zeno, Merrily Poth, Patricia Anne Deuster

Open access · diamondAbstract read
In one paragraph

Article in African health sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  5. Adipokines-A Cohort Prospective Study in Children with Severe Burns.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Preetha Anna AbrahamDepartment of Military and Emergency Medicine (MEM) Uniformed Services University of Health Sciences (USUHS) 4301 Jones Bridge Rd, Bethesda, MD 20814 (PA, SA, JK, SZ, PD).
Selasi AttipoeDepartment of Military and Emergency Medicine (MEM) Uniformed Services University of Health Sciences (USUHS) 4301 Jones Bridge Rd, Bethesda, MD 20814 (PA, SA, JK, SZ, PD).
Josh B KazmanDepartment of Military and Emergency Medicine (MEM) Uniformed Services University of Health Sciences (USUHS) 4301 Jones Bridge Rd, Bethesda, MD 20814 (PA, SA, JK, SZ, PD).
Stacey Anne ZenoDepartment of Military and Emergency Medicine (MEM) Uniformed Services University of Health Sciences (USUHS) 4301 Jones Bridge Rd, Bethesda, MD 20814 (PA, SA, JK, SZ, PD).
Merrily PothDepartment of Military and Emergency Medicine (MEM) Uniformed Services University of Health Sciences (USUHS) 4301 Jones Bridge Rd, Bethesda, MD 20814 (PA, SA, JK, SZ, PD).
Patricia Anne DeusterDepartment of Military and Emergency Medicine (MEM) Uniformed Services University of Health Sciences (USUHS) 4301 Jones Bridge Rd, Bethesda, MD 20814 (PA, SA, JK, SZ, PD).
Uniformed Services University of the Health Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is a modifiable risk factor for hypertension and T2D. Objective(s): We examined relations between fasting plasma adiponectin (ADIP), C-reactive protein (CRP) concentrations and markers of T2D in African Americans (AA).

methodsFasting plasma ADIP, CRP, Insulin (IN), HOMA-IR, lipid profiles, body fat percent (%BF), waist circumference (WC), body mass index (BMI) and blood pressure measures were determined in AA women (W: n=77) and men (M: n=34). Participants were classified into: 1) Normal fasting glucose (FG) and Normal %BF; 2) Normal FG and High %BF; and 3) High FG.

resultsCompared to men, women had significantly higher mean ADIP (W: 31.4±2.9 vs. M: 18.0±4.4 ng/L), CRP (W: 3.2±0.3 vs. M: 2.0±0.5 mg/L), %BF (W: 41.2±0.9 vs. M: 27.2±1.3), and BMI (W: 32.3±0.7 vs. M: 29.2±1.1 kg/m2). Women with normal FG and %BF had significantly higher ADIP (64.0±6.0) and lower CRP (1.3±0.6) concentrations than normal FG/ high %BF (ADIP: 37.0±5.0 and CRP: 3.1 ±0.5) and high FG (ADIP: 15.1±4.1 and CRP: 4.0 ± 0.5) groups. Women with high ADIP to CRP ratio had favorable metabolic and anthropometric profiles.

conclusionLow ADIP and high CRP are associated with excessive %BF and FG in AA women. ADIP/CRP, may be useful for detecting metabolic dysregulation.

Indexed as

AdiponectinAdultBiomarkersBlack or African AmericanBlood GlucoseBody Mass IndexCholesterol, HDLC-Reactive ProteinDiabetes Mellitus, Type 2FastingFemaleHumansInsulinMaleMiddle AgedObesityAdiponectinADIPOQ protein, humanBiomarkersBlood GlucoseCholesterol, HDLC-Reactive ProteinInsulininflammationObesitytype 2 diabetes

Identifiers

PMID29026382
PMCPMC5636261
OpenAlexW2617742213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.