ArticleThe journal of venomous animals and toxins including tropical diseases2017
Preliminary molecular characterization of a proinflammatory and nociceptive molecule from the
Article in The journal of venomous animals and toxins including tropical diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- Sea urchin granuloma: A case of marine-related injury.JAAD case reports · 2025Article
- Prickly Defenders: A Review of Venomous Sea Urchins (Echinoidea).Marine drugs · 2025Review
- Article
- Neglected Venomous Animals and Toxins: Underrated Biotechnological Tools in Drug Development.Toxins · 2021Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSea urchins are animals commonly found on the Brazilian shoreline, being
methods
resultsOne molecule could be isolated and related to the inflammatory and nociceptive activity. Regarding inflammation, increase in adherent and migrating cells was observed in the cremaster muscle after the administration of the molecule. Corroborating the inflammatory response, paw edema was also observed, although only in 20% of controls and 20 min after injection. Additionally, this molecule was able to decrease significantly the pain threshold, characterizing hyperalgesia. This molecule was analyzed by mass spectrometry, and according to the exact molecular mass, isotopic distribution and fragmentation profile, it was possible to propose the molecular formula C
conclusionsOne isolated molecule from the spine extract of
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.