ArticleScientific reports2017
Characterization and genomic study of "phiKMV-Like" phage PAXYB1 infecting Pseudomonas aeruginosa.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 31 citations in OpenAlex.
- A comprehensive analysis of the kinetics of infection of lytic bacteriophages specific to the ESKAPE and critical pathogens.World journal of microbiology & biotechnology · 2026Review
- Pseudomonas aeruginosa as a model bacterium in antiphage defense research.FEMS microbiology reviews · 2025Review
- Isolation, Characterization, and Genome Engineering of a LyticMicroorganisms · 2024Article
- A Novel Bacteriophage Infecting Multi-Drug- and Extended-Drug-ResistantAntibiotics (Basel, Switzerland) · 2024Article
- Article
- Enrichment Culture but Not Metagenomic Sequencing Identified a Highly Prevalent Phage InfectingMicrobiology spectrum · 2023Article
- Monitoring phage-induced lysis of gram-negatives in real time using a fluorescent DNA dye.Scientific reports · 2023Article
- Isolation and characterization of lytic bacteriophages againstIranian journal of microbiology · 2022Article
- Characterization and Genomic Analysis of a Novel Drexlervirial Bacteriophage IME268 with Lytic Activity AgainstInfection and drug resistance · 2022Article
- Phage-resistantFrontiers in microbiology · 2022Article
- The Bacteriophage Pf-10-A Component of the Biopesticide "Multiphage" Used to Control Agricultural Crop Diseases Caused byViruses · 2021Article
- Novel Lytic Phages Protect Cells and Mice againstJournal of virology · 2021Article
- Molecular Characteristics of Novel Phage vB_ShiP-A7 Infecting Multidrug-ResistantFrontiers in microbiology · 2021Article
- Characterization and Complete Genome Analysis of Pseudomonas aeruginosa Bacteriophage vB_PaeP_LP14 Belonging to Genus Litunavirus.Current microbiology · 2020Article
- Draft genome sequence data of a T7like phage 3A_8767 isolated from wastewater of a butcher house near Palar river.Data in brief · 2020Article
- Lying in Wait: Modeling the Control of Bacterial Infections via Antibiotic-Induced Proviruses.mSystems · 2019Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteriophage PAXYB1 was recently isolated from wastewater samples. This phage was chosen based on its lytic properties against clinical isolates of Pseudomonas aeruginosa (P. aeruginosa). In the present study, characterized PAXYB1, clarified its morphological and lytic properties, and analyzed its complete genome sequence. Based on the morphology of PAXYB1, it is a Podoviridae. The linear GC-rich (62.29%) double-stranded DNA genome of PAXYB1 is 43,337 bp including direct terminal repeats (DTRs) of 468 bp. It contains 60 open reading frames (ORFs) that are all encoded within the same strand. We also showed that PAXYB1 is a virulent phage and a new member of the phiKMV-like phages genus. Twenty-eight out of sixty predicted gene products (gps) showed significant homology to proteins of known function, which were confirmed by analyzing the structural proteome. Altogether, our work identified a novel lytic bacteriophage that lyses P. aeruginosa PAO1 and efficiently infects and kills several clinical isolates of P. aeruginosa. This phage has potential for development as a biological disinfectant to control P. aeruginosa infections.
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