ArticleScientific reports2017
Controlled delivery and minimally invasive imaging of stem cells in the lung.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 42 citations in OpenAlex.
- CD207-Positive Dendritic Cells Promote Emphysema Through CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A Minimally Invasive Robotic Tissue Palpation Device.IEEE transactions on bio-medical engineering · 2024Article
- Alveolar Organoids in Lung Disease Modeling.Biomolecules · 2024Review
- Technique for xenogeneic cross-circulation to support human donor lungs ex vivo.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023Article
- Opto-electromechanical quantification of epithelial barrier function in injured and healthy airway tissues.APL bioengineering · 2023Article
- Imaging drug delivery to the lungs: Methods and applications in oncology.Advanced drug delivery reviews · 2023Review
- Advances in lung bioengineering: Where we are, where we need to go, and how to get there.Frontiers in transplantation · 2023Review
- Imaging-guided bioreactor for de-epithelialization and long-term cultivation ofLab on a chip · 2022Article
- Homogeneous Distribution of Exogenous Cells onto De-epithelialized Rat Trachea via Instillation of Cell-Loaded Hydrogel.ACS biomaterials science & engineering · 2022Article
- Review
- Non-destructive vacuum-assisted measurement of lung elastic modulus.Acta biomaterialia · 2021Article
- Cellular Therapy for the Treatment of Paediatric Respiratory Disease.International journal of molecular sciences · 2021Review
- Harnessing organs-on-a-chip to model tissue regeneration.Cell stem cell · 2021Review
- Therapeutic Potential of Mesenchymal Stem Cells and Their Products in Lung Diseases-Intravenous Administration versus Inhalation.Pharmaceutics · 2021Review
- Proposed Mechanisms of Targeting COVID-19 by Delivering Mesenchymal Stem Cells and Their Exosomes to Damaged Organs.Stem cell reviews and reports · 2021Review
- Human-scale lung regeneration based on decellularized matrix scaffolds as a biologic platform.Surgery today · 2020Review
- The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future.Cell stem cell · 2020Review
- Bioengineering of Pulmonary Epithelium With Preservation of the Vascular Niche.Frontiers in bioengineering and biotechnology · 2020Review
- Regeneration of severely damaged lungs using an interventional cross-circulation platform.Nature communications · 2019Article
- Cell replacement in human lung bioengineering.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Intratracheal delivery of stem cells into injured or diseased lungs can provide a variety of therapeutic and immunomodulatory effects for the treatment of acute lung injury and chronic lung disease. While the efficacy of this approach depends on delivering the proper cell dosage into the target region of the airway, tracking and analysis of the cells have been challenging, largely due to the limited understanding of cell transport and lack of suitable cell monitoring techniques. We report on the transport and deposition of intratracheally delivered stem cells as well as strategies to modulate the number of cells (e.g., dose), topographic distribution, and region-specific delivery in small (rodent) and large (porcine and human) lungs. We also developed minimally invasive imaging techniques for real-time monitoring of intratracheally delivered cells. We propose that this approach can facilitate the implementation of patient-specific cells and lead to enhanced clinical outcomes in the treatment of lung disease with cell-based therapies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.