Evidence map›Paper›PMID 29025970›Full record

ArticleJournal of cell science2017

The Arf GEF GBF1 and Arf4 synergize with the sensory receptor cargo, rhodopsin, to regulate ciliary membrane trafficking.

Jing Wang, Theresa Fresquez, Vasundhara Kandachar, Dusanka Deretic

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Arfs on the Golgi: four conductors, one orchestra.Frontiers in molecular biosciences · 2025
    Review
  6. Review
  7. Article
  8. Mechanisms of regulating NIS transport to the cell membrane and redifferentiation therapy in thyroid cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Review
  9. Article
  10. Article
  11. Functional compartmentalization of photoreceptor neurons.Pflugers Archiv : European journal of physiology · 2021
    Review
  12. Review
  13. Compartmentalization of Photoreceptor Sensory Cilia.Frontiers in cell and developmental biology · 2021
    Review
  14. Review
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jing WangDepartment of Surgery, Division of Ophthalmology, University of New Mexico, Albuquerque, New Mexico 87131, USA.
Theresa FresquezDepartment of Surgery, Division of Ophthalmology, University of New Mexico, Albuquerque, New Mexico 87131, USA.
Vasundhara KandacharDepartment of Surgery, Division of Ophthalmology, University of New Mexico, Albuquerque, New Mexico 87131, USA.
Dusanka DereticDepartment of Surgery, Division of Ophthalmology, University of New Mexico, Albuquerque, New Mexico 87131, USA dderetic@salud.unm.edu.ORCID http://orcid.org/0000-0002-0795-1672
University of New Mexico · US

Funding

Rhodopsin Trafficking & Photoreceptor Membrane RenewalR01EY012421 · NEI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI DERETIC, DUSANKA DANIELLE · 1999 to 2023
$7.2M
NEI NIH HHS R01 EY012421
6 · The paper itself

Abstract

The small GTPase Arf4 and the Arf GTPase-activating protein (GAP) ASAP1 cooperatively sequester sensory receptor cargo into transport carriers targeted to primary cilia, but the input that drives Arf4 activation in this process remains unknown. Here, we show, by using frog retinas and recombinant human proteins, that during the carrier biogenesis from the photoreceptor Golgi/

Indexed as

Adaptor Proteins, Signal TransducingADP-Ribosylation FactorsAnimalsCiliaGuanine Nucleotide Exchange FactorsMicrotubule-Associated ProteinsProtein Transportrab GTP-Binding ProteinsRetinaRhodopsinSensory Receptor CellsXenopusXenopus ProteinsAdaptor Proteins, Signal TransducingADP-Ribosylation FactorsArf4 protein, XenopusGuanine Nucleotide Exchange FactorsMap9 protein, XenopusMicrotubule-Associated Proteinsrab GTP-Binding ProteinsRhodopsinXenopus ProteinsArf GTPasesCiliumRhodopsinSensory receptors

Identifiers

PMID29025970
PMCPMC5769590
OpenAlexW2763157882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.