Evidence map›Paper›PMID 29025965›Full record

ArticlePediatrics2017

Inherited IL-12Rβ1 Deficiency in a Child With BCG Adenitis and Oral Candidiasis: A Case Report.

Nevin Hatipoglu, B Haluk Güvenç, Caroline Deswarte, Kaya Koksalan, Stéphanie Boisson-Dupuis, Jean-Laurent Casanova, Jacinta Bustamante

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Human immunity to fungal infections.The Journal of experimental medicine · 2025
    Review
  4. Interferon Gamma in Sickness Predisposing toBalkan medical journal · 2024
    Review
  5. Article
  6. Article
  7. Autosomal recessiveFrontiers in immunology · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 3 countries.

Nevin HatipogluPediatrics Unit and naydin9@mynet.com.
B Haluk GüvençPediatric Surgery Unit, Bakirkoy Dr Sadi Konuk Education and Training Hospital, Istanbul, Turkey.
Caroline DeswarteLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Imagine Institute.
Kaya KoksalanLaboratory of Molecular Tuberculosis Epidemiology, Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey.
Stéphanie Boisson-DupuisLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Imagine Institute.
Jean-Laurent CasanovaLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Imagine Institute.
Jacinta BustamanteLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Imagine Institute.
Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi · TRDélégation Paris 5 · FRHoward Hughes Medical Institute · USInstitut des Maladies Génétiques Imagine · FRIstanbul University · TRPediatrics and Genetics · USRockefeller University · US

Funding

Genome-Wide Dissection of Mendelian Susceptibility to Mycobacterial DiseaseR37AI095983 · NIAID · ROCKEFELLER UNIVERSITY · PI CASANOVA, JEAN-LAURENT · 2011 to 2020
$4.6M
NIAID NIH HHS R37 AI095983
6 · The paper itself

Abstract

Tuberculosis is a major worldwide problem, and protection from it is achieved mainly by live attenuated bacille Calmette-Guérin vaccine, which is capable of causing disease in immunocompromised host. Oral thrush is abnormal in healthy children, which suggests an underlying immunodeficiency. Mendelian susceptibility to mycobacterial disease is a rare primary immunodeficiency characterized by a selective predisposition to weakly virulent

Indexed as

BCG VaccineCandidiasis, OralChild, PreschoolFemaleHumansLymphadenitisPedigreeReceptors, Interleukin-12BCG VaccineIL12RB1 protein, humanReceptors, Interleukin-12

Identifiers

PMID29025965
PMCPMC5654388
OpenAlexW2763257422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.