Trial reportJournal of applied physiology (Bethesda, Md. : 1985)2018
A novel single-beat approach to assess right ventricular systolic function.
Trial report in Journal of applied physiology (Bethesda, Md. : 1985), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07531602 (The Effect of Positive End-Expiratory Pressure on Biventricular Mechanics in the Perioperative Setting), which is not on this map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Positive End-Expiratory Pressure on Biventricular Mechanics in the Perioperative Setting
Who cites it
31 citing papers in PubMed, 50 citations in OpenAlex.
- Patient-Specific Lumped-Parameter Model for Quantifying Vessel-Specific Remodeling and Predicting Right Ventricular Function in Pulmonary Hypertension.Comprehensive Physiology · 2026Article
- Right Ventricular Dysfunction in Lung Disease/Hypoxia-Associated Pulmonary Hypertension.Journal of the American Heart Association · 2025Article
- Volume calibration with cardiac MRI versus hypertonic saline for right ventricular pressure-volume loops with exercise: Impact on ventricular function and ventricular-vascular coupling.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2025Article
- Echocardiographic assessment and new advances of right ventricle function in rats with pulmonary hypertension.Frontiers in pharmacology · 2025Review
- An Unsupervised Approach to Derive Right Ventricular Pressure-Volume Loop Phenotypes in Pulmonary Hypertension.Pulmonary circulation · 2025Article
- Intraoperative right ventricular end-systolic pressure-volume loop analysis in patients undergoing cardiac surgery: A proof-of-concept methodology.JTCVS open · 2024Article
- Right Ventricular Pressure Waveform Analysis-Clinical Relevance and Future Directions.Journal of cardiothoracic and vascular anesthesia · 2024Review
- Intrinsic mechanisms of right ventricular autoregulation.Scientific reports · 2024Article
- Exploratory analysis of the accuracy of echocardiographic parameters for the assessment of right ventricular function and right ventricular-pulmonary artery coupling.Pulmonary circulation · 2024Article
- Integrating Right Ventricular Pressure Waveform Analysis With Two-Point Volume Measurement for Quantification of Systolic and Diastolic Function: Experimental Validation and Clinical Application.Journal of cardiothoracic and vascular anesthesia · 2023Observational
- Combined use of right ventricular coupling and pulmonary arterial elastance as a comprehensive stratification approach for right ventricular function.Clinical and translational science · 2023Article
- A new assessment method for right ventricular diastolic function using right heart catheterization by pressure-volume loop.Physiological reports · 2023Article
- The sine transform is theFrontiers in cardiovascular medicine · 2023Article
- Pressure-based beat-to-beat right ventricular ejection fraction and Tau from continuous measured ventricular pressures in COVID-19 ARDS patients.Pulmonary circulation · 2023Article
- Accuracy of Swan‒Ganz catheterization-based assessment of right ventricular function: Validation study using high-fidelity micromanometry-derived values as reference.Pulmonary circulation · 2022Article
- Multimodality Deep Phenotyping Methods to Assess Mechanisms of Poor Right Ventricular-Pulmonary Artery Coupling.Function (Oxford, England) · 2022Article
- Invasive Right Ventricular Pressure-Volume Analysis: Basic Principles, Clinical Applications, and Practical Recommendations.Circulation. Heart failure · 2022Article
- Ventricular-vascular coupling is predictive of adverse clinical outcome in paediatric pulmonary arterial hypertension.Open heart · 2021Article
- Interferon-β-Induced Pulmonary Arterial Hypertension: Approach to Diagnosis and Clinical Monitoring.JACC. Case reports · 2021Article
- Estrogen receptor-α prevents right ventricular diastolic dysfunction and fibrosis in female rats.American journal of physiology. Heart and circulatory physiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Clinical assessment of right ventricular (RV) contractility in diseases such as pulmonary arterial hypertension (PAH) has been hindered by the lack of a robust methodology. Here, a novel, clinically viable, single-beat method was developed to assess end-systolic elastance (E
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.