Evidence map›Paper›PMID 29025767›Full record

Trial reportClinical cancer research : an official journal of the American Association for Cancer Research2017

Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab.

Jakub Krejcik, Kris A Frerichs, Inger S Nijhof, Berris van Kessel, Jeroen F van Velzen, Andries C Bloem, Marloes E C Broekmans, Sonja Zweegman, Johan van Meerloo, René J P Musters and 8 more

Abstract readClinical Trial, Phase IIClinical Trial, Phase III
In one paragraph

Trial report in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 1 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 1 synthesis or guideline pooled it, 167 citations in OpenAlex.

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42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 3 countries.

Jakub KrejcikDepartment of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
Kris A FrerichsDepartment of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
Inger S NijhofDepartment of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
Berris van KesselDepartment of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
Jeroen F van VelzenLaboratory for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands.
Andries C BloemLaboratory for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands.
Marloes E C BroekmansDepartment of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
Sonja ZweegmanDepartment of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
Johan van MeerlooDepartment of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
René J P MustersDepartment of Physiology, VU University, Amsterdam, the Netherlands.
Pino J PoddigheDepartment of Clinical Genetics, VU University Medical Center, Amsterdam, the Netherlands.
Richard W J GroenDepartment of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
Christopher ChiuJanssen Research and Development, Spring House, Pennsylvania.
Torben PlesnerVejle Hospital and University of Southern Denmark, Vejle, Denmark.
Henk M LokhorstDepartment of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
A Kate SasserJanssen Research and Development, Spring House, Pennsylvania.
Tuna MutisDepartment of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
Niels W C J van de DonkDepartment of Hematology, VU University Medical Center, Amsterdam, the Netherlands. n.vandedonk@vumc.nl.
Amsterdam UMC Location Vrije Universiteit Amsterdam · NLSpringhouse · USUniversity Medical Center Utrecht · NLUniversity of Southern Denmark · DK

Funding

Humanized bone marrow-like model to study patient-derived myeloma xenograftsR01CA196664 · NCI · DANA-FARBER CANCER INST · PI GROEN, RICHARD, MITSIADES, CONSTANTINE S. · 2016 to 2018
$1.6M
NCI NIH HHS R01 CA196664
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ADP-ribosyl Cyclase 1AgedAntibodies, MonoclonalB-LymphocytesCell Line, TumorDexamethasoneFemaleGene Expression Regulation, NeoplasticGranulocytesHumansKiller Cells, NaturalLenalidomideMaleMiddle AgedMonocytesMultiple MyelomaADP-ribosyl Cyclase 1Antibodies, MonoclonaldaratumumabDexamethasoneLenalidomideThalidomide

Identifiers

PMID29025767
PMCPMC5732844
OpenAlexW2764340845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.