Evidence map›Paper›PMID 29025749›Full record

ArticleJournal of the American Heart Association2017

Late Onset Postcapillary Pulmonary Hypertension in Patients With Transposition of the Great Arteries and Mustard or Senning Baffles.

Marie-A Chaix, Annie Dore, Lise-Andrée Mercier, François-Pierre Mongeon, François Marcotte, Réda Ibrahim, Anita W Asgar, Azadeh Shohoudi, Fabien Labombarda, Blandine Mondésert and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Marie-A ChaixAdult Congenital Heart Centre, Montreal Heart Institute, Université de Montréal, Quebec, Canada.
Annie DoreAdult Congenital Heart Centre, Montreal Heart Institute, Université de Montréal, Quebec, Canada.
Lise-Andrée MercierAdult Congenital Heart Centre, Montreal Heart Institute, Université de Montréal, Quebec, Canada.
François-Pierre MongeonAdult Congenital Heart Centre, Montreal Heart Institute, Université de Montréal, Quebec, Canada.
François MarcotteAdult Congenital Heart Centre, Montreal Heart Institute, Université de Montréal, Quebec, Canada.
Réda IbrahimAdult Congenital Heart Centre, Montreal Heart Institute, Université de Montréal, Quebec, Canada.
Anita W AsgarAdult Congenital Heart Centre, Montreal Heart Institute, Université de Montréal, Quebec, Canada.
Azadeh ShohoudiMontreal Health Innovation Coordinating Centre (MHICC), Montreal, Quebec, Canada.
Fabien LabombardaAdult Congenital Heart Centre, Montreal Heart Institute, Université de Montréal, Quebec, Canada.
Blandine MondésertAdult Congenital Heart Centre, Montreal Heart Institute, Université de Montréal, Quebec, Canada.
Nancy PoirierAdult Congenital Heart Centre, Montreal Heart Institute, Université de Montréal, Quebec, Canada.
Paul KhairyAdult Congenital Heart Centre, Montreal Heart Institute, Université de Montréal, Quebec, Canada paul.khairy@umontreal.ca.
Montreal Heart Institute · CAUniversité de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a paucity of data regarding late-onset pulmonary hypertension (PH) in patients with transposition of the great arteries and atrial switch surgery. METHODS AND

resultsA retrospective cohort study was conducted on 140 adults with transposition of the great arteries and atrial switch surgery, age 37.3±7.8, 37.1% female, in order to assess the prevalence and characteristics of late-onset PH and explore associated factors. Patients were followed for a median of 32.3 years after atrial switch surgery and 10.0 years after their first referral visit. PH was detected in 18 of 33 (54.5%) patients who had invasive hemodynamic studies. Average age at diagnosis of PH was 33.9±8.1 years. PH was postcapillary in all, with a mean pulmonary artery pressure of 36±12 mm Hg and mean pulmonary capillary wedge pressure of 28±8 mm Hg. PH was diagnosed in 13 of 17 (76.5%) patients who had cardiac catheterization for heart failure or decreased exercise tolerance. In multivariable analyses, systemic hypertension (odds ratio 9.4, 95% confidence interval 2.2-39.4,

conclusionsLate-onset postcapillary PH is highly prevalent in adults with transposition of the great arteries and atrial switch surgery and is associated with an adverse prognosis.

Indexed as

Arterial PressureAdultArterial Switch OperationComorbidityDisease-Free SurvivalFemaleHumansHypertension, PulmonaryKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPrevalenceProportional Hazards Modelsatrial switch surgeryMustard bafflepulmonary hypertensionSenning baffletransposition of great vessels

Identifiers

PMID29025749
PMCPMC5721856
OpenAlexW2762966638

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.