Evidence map›Paper›PMID 29025149›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2018

Segment convolutional neural networks (Seg-CNNs) for classifying relations in clinical notes.

Yuan Luo, Yu Cheng, Özlem Uzuner, Peter Szolovits, Justin Starren

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Review
  7. Article
  8. [Research on entity relationship extraction of Chinese medical literature and application in diabetes medical literature].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2021
    Article
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  15. Using UMLS for electronic health data standardization and database design.Journal of the American Medical Informatics Association : JAMIA · 2020
    Article
  16. Review
  17. Extracting entities with attributes in clinical text via joint deep learning.Journal of the American Medical Informatics Association : JAMIA · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuan LuoDepartment of Preventive Medicine, Northwestern University, Chicago, IL, USA.
Yu ChengAI Foundations, IBM Thomas J Watson Research Center, Yorktown Heights, NY, USA.
Özlem UzunerDepartment of Computer Science, State University of New York at Albany, Albany, NY, USA.
Peter SzolovitsDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
Justin StarrenDepartment of Preventive Medicine and Medical Social Science, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Informatics for Integrating Biology/ the Bedside (RMI)U54LM008748 · NLM · BRIGHAM AND WOMEN'S HOSPITAL · PI KOHANE, ISAAC S. · 2004 to 2013
$39.0M
National Infrastructure for Standardized and Portable EHR Phenotyping AlgorithmsR01GM105688 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI LUO, YUAN, PATHAK, JYOTISHMAN · 2013 to 2020
$5.7M
Natural language processing for characterizing psychopathologyR01MH106577 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI PERLIS, ROY H. · 2016 to 2018
$1.2M
Bayesian Generative Methods for Extracting and Modeling Relations in EHR NarrativesR21LM012618 · NLM · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LUO, YUAN · 2017 to 2018
$390k
NCATS NIH HHS UL1 TR001422NIGMS NIH HHS R01 GM105688NIMH NIH HHS R01 MH106577NLM NIH HHS R21 LM012618NLM NIH HHS U54 LM008748
6 · The paper itself

Abstract

We propose Segment Convolutional Neural Networks (Seg-CNNs) for classifying relations from clinical notes. Seg-CNNs use only word-embedding features without manual feature engineering. Unlike typical CNN models, relations between 2 concepts are identified by simultaneously learning separate representations for text segments in a sentence: preceding, concept1, middle, concept2, and succeeding. We evaluate Seg-CNN on the i2b2/VA relation classification challenge dataset. We show that Seg-CNN achieves a state-of-the-art micro-average F-measure of 0.742 for overall evaluation, 0.686 for classifying medical problem-treatment relations, 0.820 for medical problem-test relations, and 0.702 for medical problem-medical problem relations. We demonstrate the benefits of learning segment-level representations. We show that medical domain word embeddings help improve relation classification. Seg-CNNs can be trained quickly for the i2b2/VA dataset on a graphics processing unit (GPU) platform. These results support the use of CNNs computed over segments of text for classifying medical relations, as they show state-of-the-art performance while requiring no manual feature engineering.

Indexed as

Electronic Health RecordsNatural Language ProcessingNeural Networks, ComputerDatasets as TopicHumansMachine Learningconvolutional neural networkmachine learningmedical relation classificationnatural language processing

Identifiers

PMID29025149
PMCPMC6381760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.