ArticleJournal of the American Academy of Dermatology2018
Clinical and dermoscopic characterization of pediatric and adolescent melanomas: Multicenter study of 52 cases.
Article in Journal of the American Academy of Dermatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 52 citations in OpenAlex.
- Diagnostic Accuracy of Dermoscopy for Spitzoid Tumours in Adults.Acta dermato-venereologica · 2026Article
- Clinical-histological and genetic features of rare variants of melanoma.Histology and histopathology · 2026Review
- Pediatric Melanoma: Emerging Therapies and Ongoing Clinical Trials.Dermatology and therapy · 2026Review
- Dermoscopic Aspects of Cutaneous Melanoma and Non-Melanoma Skin Cancer.Current pharmaceutical design · 2026Review
- Gene Mutation-Negative Malignant Melanoma in a Prepubertal Patient: A Clinical and Molecular Case Report.Genes · 2025Article
- Clinical and histopathological characteristics of melanomas in Asians under age 40.Scientific reports · 2025Article
- Nevi and Melanoma in Children: What to Do in Daily Medical Practice: Encyclopedia for Pediatricians and Family Doctors.Diagnostics (Basel, Switzerland) · 2024Review
- Melanoma in Pediatric and Young Adult Patients.Current oncology reports · 2024Review
- Article
- Clinical, Dermoscopic, and Histological Characteristics of Melanoma Patients According to the Age Groups: A Retrospective Observational Study.Life (Basel, Switzerland) · 2023Article
- Article
- The Spectrum of Spitz Melanocytic Lesions: From Morphologic Diagnosis to Molecular Classification.Frontiers in oncology · 2022Review
- Understanding Skin Screening Practices Among Children at Elevated Risk for Melanoma to Inform Interventions for Melanoma Prevention and Control.Journal of cancer education : the official journal of the American Association for Cancer Education · 2020Article
- Management of Flat Pigmented Spitz and Reed Nevi in Children.JAMA dermatology · 2018Article
- Contrasting features of childhood and adolescent melanomas.Pediatric dermatology · 2018Article
- Pediatric Melanoma and Drug Development.Children (Basel, Switzerland) · 2018Article
- Acral Lentiginous Melanoma: A United States Multi-Center Substage Survival Analysis.Cancer control : journal of the Moffitt Cancer CenterArticle
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Authors and funding
11 authors at 8 institutions in 6 countries.
Funding
Abstract
backgroundKnowledge regarding the morphologic spectrum of pediatric melanoma (PM) is sparse, and this may in part contribute to delay in detection and thicker tumors.
objectiveTo analyze the clinicodermoscopic characteristics of PM.
methodsRetrospective study of 52 melanomas diagnosed in patients before the age of 20 years.
resultsOn the basis of its clinical, dermoscopic, and histopathologic characteristics, PM can be classified as spitzoid or nonspitzoid. The nonspitzoid melanomas (n = 37 [72.3%]) presented in patients with a mean age of 16.3 years (range, 8-20) and were associated with a high-risk phenotype and a pre-existing nevus (62.2%). The spitzoid melanomas (n = 15 [27.7%]) were diagnosed in patients at a mean age of 12.5 years (range, 2-19) and were mostly de novo lesions (73.3%) located on the limbs (73.3%). Whereas less than 25% of PMs fulfilled the modified clinical ABCD criteria (amelanotic, bleeding bump, color uniformity, de novo at any diameter), 40% of spitzoid melanomas did. Dermoscopic melanoma criteria were found in all cases. Nonspitzoid melanomas tended to be multicomponent (58.3%) or have nevus-like (25%) dermoscopic patterns. Spitzoid melanomas revealed atypical vascular patterns with shiny white lines (46.2%) or an atypical pigmented spitzoid pattern (30.8%). There was good correlation between spitzoid subtype histopathologically and dermoscopically (κ = 0.66). LIMITATIONS: A retrospective study without re-review of pathologic findings.
conclusionDermoscopy in addition to conventional and modified clinical ABCD criteria helps in detecting PM. Dermoscopy assists in differentiating spitzoid from nonspitzoid melanomas.
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