ArticleBipolar disorders2018
Reduced electroencephalogram responses to standard and target auditory stimuli in bipolar disorder and the impact of psychotic features: Analysis of event-related potentials, spectral power, and inter-trial coherence.
Article in Bipolar disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Volume and Tempo: Cortical Excitability and Trial-to-Trial Consistency of Auditory Responses Distinguish Psychosis Biotypes.Research square · 2026Article
- Temporal imprecision of phase coherence in schizophrenia and psychosis-dynamic mechanisms and diagnostic marker.Molecular psychiatry · 2024Review
- Categorical and Dimensional Approaches for Psychiatric Classification and Treatment Targeting: Considerations from Psychosis Biotypes.Advances in neurobiology · 2024Review
- Modality-Attention Promotes the Neural Effects of Precise Timing Prediction in Early Sensory Processing.Brain sciences · 2023Article
- Psychosis Biotypes: Replication and Validation from the B-SNIP Consortium.Schizophrenia bulletin · 2022Article
- Reduced white matter microstructure in bipolar disorder with and without psychosis.Bipolar disorders · 2021Article
- Auditory Oddball Responses Across the Schizophrenia-Bipolar Spectrum and Their Relationship to Cognitive and Clinical Features.The American journal of psychiatry · 2021Article
- Special Report on the Impact of the COVID-19 Pandemic on Clinical EEG and Research and Consensus Recommendations for the Safe Use of EEG.Clinical EEG and neuroscience · 2021Article
- Auditory paired-stimuli responses across the psychosis and bipolar spectrum and their relationship to clinical features.Biomarkers in neuropsychiatry · 2020Article
- Electrophysiological correlates of emotional scene processing in bipolar disorder.Journal of psychiatric research · 2020Article
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4 authors.
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Abstract
backgroundBipolar disorder (BD) is associated with reductions in the P3b event-related potential (ERP) response to target auditory stimuli, which suggests deficits in context updating. Previous studies have typically examined these responses in the temporal domain, which may not capture alterations in specific frequencies of phase-locked or induced electrophysiological activity. Therefore, the present study examined early and late ERPs in temporal and frequency domains in a bipolar sample with and without current psychotic features.
methodsThe electroencephalogram (EEG) was recorded during an auditory oddball task. Seventy-five BD patients and 98 healthy controls (HCs) discriminated between standard and target tones. N1 ERPs to standards and P3b ERPs to targets were analyzed in the temporal domain. Event-related spectral perturbation (ERSP) and inter-trial coherence (ITC) were analyzed in the frequency domain.
resultsThe early N1 response to standard tones was not significantly different between the total HC and BD samples irrespective of psychotic features. However, N1 amplitude was reduced in BD patients with psychotic features (BDP) compared to HCs and BD patients without psychotic features. P3b was reduced in BD patients versus HCs, with the BDP sample having the most reduced amplitude. In the time-frequency analysis, delta and theta ERSP and ITC were reduced across the time window for both standard and target stimuli in BD patients compared to HCs, but did not differ in the psychotic features analysis.
conclusionsThe results provide neural evidence that BD is associated with disrupted sensory, attentional, and cognitive processing of auditory stimuli, which may be worsened with the presence of psychotic features.
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