Evidence map›Paper›PMID 29024289›Full record

ArticleAngewandte Chemie (International ed. in English)2017

Diastereoselective C-H Bond Amination for Disubstituted Pyrrolidines.

Diana A Iovan, Matthew J T Wilding, Yunjung Baek, Elisabeth T Hennessy, Theodore A Betley

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
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  9. Review
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  11. Article
  12. Efficient C-H Amination Catalysis Using Nickel-Dipyrrin Complexes.Journal of the American Chemical Society · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Intramolecular CspChemical science · 2020
    Article
  17. Article
  18. Article
  19. Catalytic C-H Amination Mediated by Dipyrrin Cobalt Imidos.Journal of the American Chemical Society · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Diana A IovanDepartment of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA, 02138, USA.
Matthew J T WildingDepartment of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA, 02138, USA.
Yunjung BaekDepartment of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA, 02138, USA.
Elisabeth T HennessyDepartment of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA, 02138, USA.
Theodore A BetleyDepartment of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA, 02138, USA.ORCID 0000-0001-5946-9629

Funding

Correlation of electronic structure to iron catalyzed C-H bond functionalizationR01GM115815 · NIGMS · HARVARD UNIVERSITY · PI BETLEY, THEODORE A · 2015 to 2018
$1.3M
NIGMS NIH HHS R01 GM115815
6 · The paper itself

Abstract

We report herein the improved diastereoselective synthesis of 2,5-disubstituted pyrrolidines from aliphatic azides. Experimental and theoretical studies of the C-H amination reaction mediated by the iron dipyrrinato complex (

Indexed as

AminationCatalysisFerric CompoundsMolecular StructureOxidesPyrrolidinesStereoisomerismFerric CompoundsOxidesPyrrolidinesC−H activationdiastereoselectivityironphenoxidepyrrolidine

Identifiers

PMID29024289
PMCPMC5821116

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.