ArticleHuman brain mapping2018
Association of schizotypy with striatocortical functional connectivity and its asymmetry in healthy adults.
Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Fronto-Thalamic Structural Connectivity Associated With Schizotypy, a Psychosis Risk Phenotype, in Nonclinical Subjects.Schizophrenia bulletin · 2025Article
- Negative Schizotypy Associated With Weaker Intersubject Correlation in Dynamic Functional Connectivity During Empathic Accuracy Task.Schizophrenia bulletin · 2025Article
- Neuropsychology and Neurobiology of Negative Schizotypy: A Selective Review.Biological psychiatry global open science · 2024Review
- Neural bases of reward anticipation in healthy individuals with low, mid, and high levels of schizotypy.Scientific reports · 2023Article
- Gradients of striatal function in antipsychotic-free first-episode psychosis and schizotypy.Translational psychiatry · 2023Article
- Cognitive Processes and Resting-State Functional Neuroimaging Findings in High Schizotypal Individuals and Schizotypal Personality Disorder Patients: A Systematic Review.Brain sciences · 2023Review
- Negative schizotypal traits predict the reduction of reward motivation in effort-reward imbalance.European archives of psychiatry and clinical neuroscience · 2023Article
- Frontostriatothalamic effective connectivity and dopaminergic function in the psychosis continuum.Brain : a journal of neurology · 2023Article
- Frontotemporal thalamic connectivity in schizophrenia and schizotypal personality disorder.Psychiatry research. Neuroimaging · 2022Article
- The stress-vulnerability model on the path to schizophrenia: Interaction between BDNF methylation and schizotypy on the resting-state brain network.Schizophrenia (Heidelberg, Germany) · 2022Article
- Neural Correlates of Smooth Pursuit Eye Movements in Schizotypy and Recent Onset Psychosis: A Multivariate Pattern Classification Approach.Schizophrenia bulletin open · 2022Article
- The Prediction Analysis of Autistic and Schizotypal Traits in Attentional Networks.Psychiatry investigation · 2021Article
- Schizotypy in Parkinson's disease predicts dopamine-associated psychosis.Scientific reports · 2021Article
- Psychosis risk is associated with decreased resting-state functional connectivity between the striatum and the default mode network.Cognitive, affective & behavioral neuroscience · 2019Article
- Emerging Temporal Lobe Dysfunction in People at Clinical High Risk for Psychosis.Frontiers in psychiatry · 2019Review
- Perspectives on Machine Learning for Classification of Schizotypy Using fMRI Data.Schizophrenia bulletin · 2018Article
- Increased resting perfusion of the hippocampus in high positive schizotypy: A pseudocontinuous arterial spin labeling study.Human brain mapping · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Altered striatocortical functional connectivity has been suggested to be a trait marker of schizophrenia spectrum disorders, including schizotypal personality. In the present study, we examined the association between schizotypal personality traits and striatocortical functional connectivity in a sample of healthy adults. The German version of the Schizotypal Personality Questionnaire was obtained from N = 111 participants recruited from the general public. Resting-state functional magnetic resonance imaging scans were acquired at 3T. Six striatal seed regions in each hemisphere were defined and striatocortical resting-state functional connectivity (rsFC) as well as its lateralization indices was calculated. Regression analysis showed that schizotypy scores, especially from the positive dimension, were positively correlated with rsFC between ventral striatum and frontal cortex and negatively associated with rsFC between dorsal striatum and posterior cingulate. No significant associations were found between negative dimension schizotypy and striatocortical rsFC. We also found positive correlations between schizotypy total scores and lateralization index of right dorsal caudate and right rostral putamen. In conclusion, the present study extends previous evidence of altered striatocortical rsFC in the schizophrenia spectrum. The observed associations resemble in part the alterations observed in psychotic patients and their relatives, providing support for dimensionality from schizotypal personality to the clinical disorder. Hum Brain Mapp 39:288-299, 2018. © 2017 Wiley Periodicals, Inc.
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