ArticleHuman brain mapping2018
Clinical yield of magnetoencephalography distributed source imaging in epilepsy: A comparison with equivalent current dipole method.
Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Cortical Thickness of Brain Areas Beyond Stroke Lesions and Sensory-Motor Recovery: A Systematic Review.Frontiers in neuroscience · 2021Pooled it
- Characterizing hippocampal dynamics with MEG: A systematic review and evidence-based guidelines.Human brain mapping · 2019Pooled it
- Transcranial direct current stimulation over the sensory-motor regions inhibits gamma synchrony.Human brain mapping · 2019Trial
- Complementary predictive value of electromagnetic source imaging and hemodynamic responses in epilepsy surgery: A quantitative spatial analysis.Epilepsia · 2026Article
- Magnetoencephalography distributed source modeling identifies spatiotemporal propagation patterns of interictal epileptiform discharges.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- NIRSTORM: a Brainstorm extension dedicated to functional near-infrared spectroscopy data analysis, advanced 3D reconstructions, and optimal probe design.Neurophotonics · 2025Article
- Prestimulus functional connectivity reflects attention orientation in a prospective memory task: A magnetoencephalographic (MEG) study.PloS one · 2025Article
- Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy.Journal of visualized experiments : JoVE · 2024Article
- EEG/MEG source imaging of deep brain activity within the maximum entropy on the mean framework: Simulations and validation in epilepsy.Human brain mapping · 2024Article
- Post-processing of a distributed source method for the localization of somatosensory cortex in a cohort of epilepsy patients.Neuroimage. Reports · 2024Article
- Excitation/Inhibition balance relates to cognitive function and gene expression in temporal lobe epilepsy: a high density EEG assessment with aperiodic exponent.Brain communications · 2024Article
- Electrical Source Imaging of Somatosensory Evoked Potentials from Intracranial EEG Signals.Brain topography · 2023Article
- Hierarchical Bayesian modeling of the relationship between task-related hemodynamic responses and cortical excitability.Human brain mapping · 2023Article
- From theory to practical fundamentals of electroencephalographic source imaging in localizing the epileptogenic zone.Epilepsia · 2022Review
- Novel User-Friendly Application for MRI Segmentation of Brain Resection following Epilepsy Surgery.Diagnostics (Basel, Switzerland) · 2022Article
- Sensorimotor integration within the primary motor cortex by selective nerve fascicle stimulation.The Journal of physiology · 2022Article
- Clinical Validation of the Champagne Algorithm for Evoked Response Source Localization in Magnetoencephalography.Brain topography · 2022Article
- Imaging the extent and location of spatiotemporally distributed epileptiform sources from MEG measurements.NeuroImage. Clinical · 2022Article
- Article
- How cerebral cortex protects itself from interictal spikes: The alpha/beta inhibition mechanism.Human brain mapping · 2021Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveSource localization of interictal epileptic discharges (IEDs) is clinically useful in the presurgical workup of epilepsy patients. It is usually obtained by equivalent current dipole (ECD) which localizes a point source and is the only inverse solution approved by clinical guidelines. In contrast, magnetic source imaging using distributed methods (dMSI) provides maps of the location and the extent of the generators, but its yield has not been clinically validated. We systematically compared ECD versus dMSI performed using coherent Maximum Entropy on the Mean (cMEM), a method sensitive to the spatial extent of the generators.
methods340 source localizations of IEDs derived from 49 focal epilepsy patients with foci well-defined through intracranial EEG, MRI lesions, and surgery were analyzed. The comparison was based on the assessment of the sublobar concordance with the focus and of the distance between the source and the focus.
resultsdMSI sublobar concordance was significantly higher than ECD (81% vs 69%, P < 0.001), especially for extratemporal lobe sources (dMSI = 84%; ECD = 67%, P < 0.001) and for seizure free patients (dMSI = 83%; ECD = 70%, P < 0.001). The median distance from the focus was 4.88 mm for ECD and 3.44 mm for dMSI (P < 0.001). ECD dipoles were often wrongly localized in deep brain regions.
conclusionsdMSI using cMEM exhibited better accuracy. dMSI also offered the advantage of recovering more realistic maps of the generator, which could be exploited for neuronavigation aimed at targeting invasive EEG and surgical resection. Therefore, dMSI may be preferred to ECD in clinical practice. Hum Brain Mapp 39:218-231, 2018. © 2017 Wiley Periodicals, Inc.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.