Evidence map›Paper›PMID 29023730›Full record

ArticleThe Journal of physiology2017

CrossTalk opposing view: proton transfer in Hv1 utilizes a water wire, and does not require transient protonation of a conserved aspartate in the S1 transmembrane helix.

Ashley L Bennett, Ian Scott Ramsey

Open access · greenAbstract read
In one paragraph

Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Quantitative insights into the mechanism of proton conduction and selectivity for the human voltage-gated proton channel Hv1.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Transcendent Aspects of Proton Channels.Annual review of physiology · 2024
    Review
  4. Article
  5. A family of hyperpolarization-activated channels selective for protons.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  6. Hydrophobic gasket mutation produces gating pore currents in closed human voltage-gated proton channels.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  7. Review
  8. Molecular mechanisms of coupling to voltage sensors in voltage-evoked cellular signals.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2019
    Review
  9. On the control of the proton current in the voltage-gated proton channel Hv1.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  10. Article
  11. HistidineThe Journal of general physiology · 2018
    Article
  12. Otopetrin-1: A sour-tasting proton channel.The Journal of general physiology · 2018
    Article
  13. Rebuttal from Thomas E. DeCoursey.The Journal of physiology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ashley L BennettVirginia Commonwealth University School of Medicine, Richmond, VA, USA.ORCID 0000-0001-7927-4511
Ian Scott RamseyVirginia Commonwealth University School of Medicine, Richmond, VA, USA.ORCID 0000-0002-6432-4253
Virginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ProtonsAnimalsAspartic AcidHumansIon Channel GatingIon ChannelsWaterAspartic AcidIon ChannelsProtonsWaterGrotthuss mechanismproton shuttleproton transfervoltage sensorwater wire

Identifiers

PMID29023730
PMCPMC5685820
OpenAlexW2761538144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.