Evidence map›Paper›PMID 29023392›Full record

ArticlePharmaceutics2017

Disposition, Metabolism and Histone Deacetylase and Acetyltransferase Inhibition Activity of Tetrahydrocurcumin and Other Curcuminoids.

Júlia T Novaes, Ryan Lillico, Casey L Sayre, Kalyanam Nagabushnam, Muhammed Majeed, Yufei Chen, Emmanuel A Ho, Ana Luísa de P Oliveira, Stephanie E Martinez, Samaa Alrushaid and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Safety of tetrahydrocurcuminoids from turmeric (EFSA journal. European Food Safety Authority · 2021
    Article
  10. Review
  11. Review
  12. Efficacy and Safety of Tetrahydrocurcuminoids for the Treatment of Canker Sore and Gingivitis.Evidence-based complementary and alternative medicine : eCAM · 2020
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Júlia T NovaesThe Rady Faculty of Health Sciences, College of Pharmacy, Pharmaceutical Analysis Laboratory, University of Manitoba, Winnipeg, MB R3E 0T5, Canada. juliatnovaes@gmail.com.
Ryan LillicoThe Rady Faculty of Health Sciences, College of Pharmacy, Pharmaceutical Analysis Laboratory, University of Manitoba, Winnipeg, MB R3E 0T5, Canada. umLillic@myumanitoba.ca.ORCID 0000-0002-9486-9254
Casey L SayreCollege of Pharmacy, Roseman University of Health Sciences, South Jordan, UT 84096, USA. csayre@roseman.edu.ORCID 0000-0002-1820-7689
Kalyanam NagabushnamSabinsa Corporation, 20 Lake Drive, East Windsor, NJ 08520, USA. kalyanam@sabinsa.com.ORCID 0000-0001-9470-4110
Muhammed MajeedSabinsa Corporation, 20 Lake Drive, East Windsor, NJ 08520, USA. mmjd52@hotmail.com.
Yufei ChenThe Rady Faculty of Health Sciences, College of Pharmacy, Pharmaceutical Analysis Laboratory, University of Manitoba, Winnipeg, MB R3E 0T5, Canada. umche355@myumanitoba.ca.ORCID 0000-0002-5782-3556
Emmanuel A HoFaculty of Science, School of Pharmacy, University of Waterloo, Kitchener, ON N2G 1C5, Canada. emmanuel.ho@uwaterloo.ca.
Ana Luísa de P OliveiraThe Rady Faculty of Health Sciences, College of Pharmacy, Pharmaceutical Analysis Laboratory, University of Manitoba, Winnipeg, MB R3E 0T5, Canada. analuisapoliv@gmail.com.
Stephanie E MartinezDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610, USA. smartinez@vetmed.wsu.edu.
Samaa AlrushaidThe Rady Faculty of Health Sciences, College of Pharmacy, Pharmaceutical Analysis Laboratory, University of Manitoba, Winnipeg, MB R3E 0T5, Canada. umalrush@myumanitoba.ca.ORCID 0000-0001-7705-9025
Neal M DaviesFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2R3, Canada. ndavies@ualberta.ca.
Ted M LakowskiThe Rady Faculty of Health Sciences, College of Pharmacy, Pharmaceutical Analysis Laboratory, University of Manitoba, Winnipeg, MB R3E 0T5, Canada. ted.lakowski@umanitoba.ca.
University of Manitoba · CASabin Vaccine Institute · USRoseman University of Health Sciences · USUniversity of Alberta · CAUniversity of Waterloo · CAWashington State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tetrahydrocurcumin (THC), curcumin and calebin-A are curcuminoids found in turmeric (

Indexed as

anticanceranti-inflammatoryantioxidantcalebin-AcurcuminHATHDACpharmacokineticstetrahydrocurcuminUHPLC–MS/MS

Identifiers

PMID29023392
PMCPMC5750651
OpenAlexW2762766132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.