Evidence map›Paper›PMID 29023307›Full record

Observational studyJournal of clinical neurophysiology : official publication of the American Electroencephalographic Society2017

Interrater Agreement of EEG Interpretation After Pediatric Cardiac Arrest Using Standardized Critical Care EEG Terminology.

Nicholas S Abend, Shavonne L Massey, Mark Fitzgerald, France Fung, Natalie J Atkin, Rui Xiao, Alexis A Topjian

Abstract readObservational Study
In one paragraph

Observational study in Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Unveiling variability: A systematic review of reproducibility in visual EEG analysis, with focus on seizures.Epileptic disorders : international epilepsy journal with videotape · 2024
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Observational
  6. Observational
  7. Article
  8. Article
  9. Early EEG Features for Outcome Prediction After Cardiac Arrest in Children.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2019
    Observational
  10. Observational
  11. EEG Factors After Pediatric Cardiac Arrest.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2018
    Observational
  12. Article
  13. Stability of Early EEG Background Patterns After Pediatric Cardiac Arrest.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2018
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nicholas S AbendDepartments of *Neurology, †Pediatrics, and ‡Anesthesia and Critical Care Medicine, Children's Hospital of Philadelphia and the University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.; and §Center for Clinical Epidemiology and Biostatistics, Philadelphia, Pennsylvania, U.S.A.
Shavonne L Massey
Mark Fitzgerald
France Fung
Natalie J Atkin
Rui Xiao
Alexis A Topjian

Funding

The Intellectual and Developmental Disabilities Research Center at CHOP/PennU54HD086984 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI ROBERTS, TIMOTHY P · 2016 to 2020
$6.3M
Neurologic Clinical Epidemiology Training ProgramT32NS061779 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Andrea Lauren Christman Schneider, Allison Willis · 2008 to 2026
$4.6M
Prompt Diagnosis and Treatment of Subclinical Seizures After Cardiac ArrestK23NS075363 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI TOPJIAN, ALEXIS A. · 2012 to 2016
$874k
Electrographic seizure management and neurobehavioral outcomes in critically ill children.K02NS096058 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI ABEND, NICHOLAS SCOTT · 2017 to 2019
$579k
NICHD NIH HHS U54 HD086984NINDS NIH HHS K02 NS096058NINDS NIH HHS K23 NS075363NINDS NIH HHS T32 NS061779
6 · The paper itself

Abstract

purposeWe evaluated interrater agreement of EEG interpretation in a cohort of critically ill children resuscitated after cardiac arrest using standardized EEG terminology.

methodsFour pediatric electroencephalographers scored 10-minute EEG segments from 72 consecutive children obtained 24 hours after return of circulation using the American Clinical Neurophysiology Society's (ACNS) Standardized Critical Care EEG terminology. The percent of perfect agreement and the kappa coefficient were calculated for each of the standardized EEG variables and a predetermined composite EEG background category.

resultsThe overall background category (normal, slow-disorganized, discontinuous, or attenuated-featureless) had almost perfect agreement (kappa 0.89).The ACNS Standardized Critical Care EEG variables had agreement that was (1) almost perfect for the seizures variable (kappa 0.93), (2) substantial for the continuity (kappa 0.79), voltage (kappa 0.70), and sleep transient (kappa 0.65) variables, (3) moderate for the rhythmic or periodic patterns (kappa 0.55) and interictal epileptiform discharge (kappa 0.60) variables, and (4) fair for the predominant frequency (kappa 0.23) and symmetry (kappa 0.31) variables. Condensing variable options led to improved agreement for the continuity and voltage variables.

conclusionsThese data support the use of the standardized terminology and the composite overall background category as a basis for standardized EEG interpretation for subsequent studies assessing EEG background for neuroprognostication after pediatric cardiac arrest.

Indexed as

Critical CareElectroencephalographyTerminology as TopicBrainChildChild, PreschoolCohort StudiesFemaleHeart ArrestHumansInfantMaleObserver VariationProspective Studies

Identifiers

PMID29023307
PMCPMC5679731

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.