ArticlePreventing chronic disease2017
Early Onset Obesity and Risk of Metabolic Syndrome Among Chilean Adolescents.
Article in Preventing chronic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Proteomic Insights into Childhood Obesity: A Systematic Review of Protein Biomarkers and Advances.International journal of molecular sciences · 2025Pooled it
- Impact of Setmelanotide on Metabolic Syndrome Risk in Patients With Bardet-Biedl Syndrome.The Journal of clinical endocrinology and metabolism · 2025Trial
- Study Design and Conceptual Framework of an Observational Study of Food Insecurity and Life's Essential 8 in College Students: The FRESH Study.Journal of the American Heart Association · 2026Observational
- Supervised Machine Learning Algorithms for Fitness-Based Cardiometabolic Risk Classification in Adolescents.Sports (Basel, Switzerland) · 2025Article
- Value of waist-to-hip ratio as a predictor of metabolic syndrome in adolescents with obesity.Acta bio-medica : Atenei Parmensis · 2023Article
- Infant Growth Trajectories and Lipid Levels in Adolescence: Evidence From a Chilean Infancy Cohort.American journal of epidemiology · 2022Article
- Cross-sectional association between physical fitness and cardiometabolic risk in Chilean schoolchildren: the fat but fit paradox.Translational pediatrics · 2022Article
- Omentin as an Independent Predictor of Metabolic Syndrome and Obesity Among Adolescents in Northeast China.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Resolving early obesity leads to a cardiometabolic profile within normal ranges at 23 years old in a two-decade prospective follow-up study.Scientific reports · 2021Article
- Genome-wide association study identifying novel variant for fasting insulin and allelic heterogeneity in known glycemic loci in Chilean adolescents: The Santiago Longitudinal Study.Pediatric obesity · 2021Article
- Association between theNutrients · 2021Article
- CARDIOMETABOLIC RISK AMONG MONTENEGRIN URBAN CHILDREN IN RELATION TO OBESITY AND GENDER.Acta clinica Croatica · 2021Article
- Kindergarten Obesity and Academic Achievement: The Mediating Role of Weight Bias.Frontiers in psychology · 2021Article
- An Approach to Early Detection of Metabolic Syndrome through Non-Invasive Methods in Obese Children.Children (Basel, Switzerland) · 2020Article
- Insulin Resistance in Obese Children: What Can Metabolomics and Adipokine Modelling Contribute?Nutrients · 2020Review
- Evaluation of Different Adiposity Indices and Association with Metabolic Syndrome Risk in Obese Children: Is there a Winner?International journal of molecular sciences · 2020Article
- Mechanisms linking childhood weight status to metabolic risk in adolescence.Pediatric diabetes · 2020Article
- Long-term vs. recent-onset obesity: their contribution to cardiometabolic risk in adolescence.Pediatric research · 2019Article
- Eating in the Absence of Hunger and Obesity Among Adolescents in Santiago, Chile.Journal of community health · 2019Article
- Infant Psychosocial Environment Predicts Adolescent Cardiometabolic Risk: A Prospective Study.The Journal of pediatrics · 2019Article
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Authors and funding
6 authors.
Funding
Abstract
introductionObesity and metabolic syndrome (MetS) indicators have increased globally among the pediatric population. MetS indicators in the young elevate their risk of cardiovascular disease and metabolic disorders later in life. This study examined early onset obesity as a risk factor for MetS risk in adolescence.
methodsA cohort of Chilean participants (N = 673) followed from infancy was assessed at age 5 years and in adolescence (mean age, 16.8 y). Adiposity was measured at both time points; blood pressure and fasting blood samples were assessed in adolescence only. Early onset obesity was defined as a World Health Organization z score of 2 standard deviations (SDs) or more for body mass index (BMI) at age 5 years. We used linear regression to examine the association between early onset obesity and adolescent MetS risk z score, adjusting for covariates.
resultsEighteen percent of participants had early onset obesity, and 50% of these remained obese in adolescence. Mean MetS risk z score in adolescence was significantly higher among those with early onset obesity than among those without (1.0; SD, 0.8 vs 0.2; SD, 0.8 [P < .001]). In the multivariable model, early onset obesity independently contributed to a higher MetS risk score in adolescence (β = 0.27, P < .001), controlling for obesity status at adolescence and sex, and explained 39% of the variance in MetS risk.
conclusionEarly onset obesity as young as age 5 years relates to higher MetS risk.
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