Evidence map›Paper›PMID 29022912›Full record

ArticleCell death & disease2017

Tenomodulin is essential for prevention of adipocyte accumulation and fibrovascular scar formation during early tendon healing.

Dasheng Lin, Paolo Alberton, Manuel Delgado Caceres, Elias Volkmer, Matthias Schieker, Denitsa Docheva

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 1 synthesis or guideline pooled it, 118 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Grafts in tendon repair.Materials today. Bio · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Fabrication and Characterization of Electrospun DegraPolMaterials (Basel, Switzerland) · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Mechanobiological Strategies to Enhance Ovine (Animals : an open access journal from MDPI · 2024
    Article
  18. Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Dasheng LinExperimental Surgery and Regenerative Medicine, Department of Surgery, Ludwig-Maximilians-University (LMU), Munich, Germany.
Paolo AlbertonExperimental Surgery and Regenerative Medicine, Department of Surgery, Ludwig-Maximilians-University (LMU), Munich, Germany.
Manuel Delgado CaceresExperimental Trauma Surgery, Department of Trauma Surgery, University Regensburg Medical Centre, Regensburg, Germany.
Elias VolkmerExperimental Surgery and Regenerative Medicine, Department of Surgery, Ludwig-Maximilians-University (LMU), Munich, Germany.
Matthias SchiekerExperimental Surgery and Regenerative Medicine, Department of Surgery, Ludwig-Maximilians-University (LMU), Munich, Germany.
Denitsa DochevaExperimental Trauma Surgery, Department of Trauma Surgery, University Regensburg Medical Centre, Regensburg, Germany.ORCID 0000-0002-7588-1290
Ludwig-Maximilians-Universität München · DEUniversity Hospital Regensburg · DENovartis (Switzerland) · CH

Funding

The Gene Wiki: Community intelligence applied to gene annotationR01GM089820 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI SU, ANDREW I · 2010 to 2021
$5.2M
NIGMS NIH HHS R01 GM089820
6 · The paper itself

Abstract

Tenomodulin (Tnmd) is the best-known mature marker for tendon and ligament lineage cells. It is important for tendon maturation, running performance and has key implications for the resident tendon stem/progenitor cells (TSPCs). However, its exact functions during the tendon repair process still remain elusive. Here, we established an Achilles tendon injury model in a Tnmd knockout (Tnmd

Indexed as

Achilles TendonAdipocytesAnimalsBiglycanCartilage Oligomeric Matrix ProteinCD146 AntigenCell MovementCell ProliferationCells, CulturedCicatrixFibronectinsLipoprotein LipaseMacrophagesMembrane ProteinsMiceMice, Inbred C57BLBiglycanCartilage Oligomeric Matrix ProteinCD146 AntigenFibronectinsLipoprotein LipaseMcam protein, mouseMembrane ProteinsPPAR gammaRNA, MessengerTnmd protein, mouse

Identifiers

PMID29022912
PMCPMC5682675
OpenAlexW2762872355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.