Evidence map›Paper›PMID 29022878›Full record

ArticleeLife2017

Stochastic variation in the initial phase of bacterial infection predicts the probability of survival in

David Duneau, Jean-Baptiste Ferdy, Jonathan Revah, Hannah Kondolf, Gerardo A Ortiz, Brian P Lazzaro, Nicolas Buchon

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed.

  1. Article
  2. Sex differences inProceedings of the National Academy of Sciences of the United States of America · 2026
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  9. α2-macroglobulin function of thioester-containing proteins guardsProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  11. Review
  12. Article
  13. Article
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  15. Article
  16. Standard ingredient ofMicrobiology spectrum · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

David DuneauDepartment of Entomology, Cornell University, Ithaca, United States.ORCID http://orcid.org/0000-0002-8323-1511
Jean-Baptiste FerdyLaboratoire Évolution & Diversité Biologique, UMR5174 EDB, CNRS, ENSFEA, Université Toulouse 3 Paul Sabatier, Toulouse, France.
Jonathan RevahDepartment of Entomology, Cornell University, Ithaca, United States.
Hannah KondolfDepartment of Entomology, Cornell University, Ithaca, United States.
Gerardo A OrtizDepartment of Entomology, Cornell University, Ithaca, United States.
Brian P Lazzaro *Department of Entomology, Cornell University, Ithaca, United States.
Nicolas Buchon *Department of Entomology, Cornell University, Ithaca, United States.

Funding

Genetic Network Linking Immunity to Energetic Stress, Metabolism and ReproductionR01AI083932 · NIAID · CORNELL UNIVERSITY · PI LAZZARO, BRIAN · 2009 to 2015
$2.6M
Genetic and Physiological Constraint on ImmunityR56AI083932 · NIAID · CORNELL UNIVERSITY · PI LAZZARO, BRIAN · 2017 to 2017
$248k
NIAID NIH HHS R01 AI083932NIAID NIH HHS R56 AI083932
6 · The paper itself

Abstract

A central problem in infection biology is understanding why two individuals exposed to identical infections have different outcomes. We have developed an experimental model where genetically identical, co-housed

Indexed as

Host-Pathogen InteractionsAnimalsBacterial InfectionsDisease Models, AnimalDrosophila melanogasterSurvival AnalysisD. melanogasterevolutionary biologygenomicsImd pathwayinfectious diseaseinnate immunityinter-individual variationmicrobiologymixture modellingstochasticity

Identifiers

PMID29022878
PMCPMC5703640

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.