ReviewNature reviews. Cardiology2018
Epidemiology of cardiovascular disease in young individuals.
Review in Nature reviews. Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 365 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
365 citing papers in PubMed, 3 syntheses or guidelines pooled it, 681 citations in OpenAlex.
- The relationship between cardiovascular health and common mental disorders among adults aged ≤ 50 years: a systematic review of observational studies.BMC psychiatry · 2026Pooled it
- Association between diabetes mellitus and primary restenosis following endovascular treatment: a comprehensive meta-analysis of randomized controlled trials.Cardiovascular diabetology · 2024Pooled it
- Intestinal permeability in human cardiovascular diseases: a systematic review and meta-analysis.Frontiers in nutrition · 2024Pooled it
- Effects of thigh muscle activity patterns on blood pressure and edema during interrupted sitting in overweight and obese men.European journal of applied physiology · 2026Trial
- Effects of different training modes on hemodynamics and vascular endothelial function in young obese adults.Scientific reports · 2025Trial
- Acute night shift work is associated with increased blood pressure and reduced sleep duration in healthy adults.Physiological reports · 2025Trial
- A perinatal coparenting intervention: Effects of a randomized trial on parent cardiometabolic risk and self-reported health.Biological psychology · 2023Trial
- Weight gain prevention interventions in the Study of Novel Approaches to Weight Gain Prevention (SNAP) trial promote ideal cardiovascular health in young adults.Obesity (Silver Spring, Md.) · 2023Trial
- Early-onset atherosclerotic cardiovascular disease in young adults: Lifestyle, environmental, and psychosocial risk factors.International journal of cardiology. Cardiovascular risk and prevention · 2026Review
- Cardiovascular health and depression among postpartum women in the United States.American journal of preventive cardiology · 2026Article
- A diagnostic and classification model integrating cTnI, CK-MB, MYO and NT-proBNP for cardiovascular diseases.Experimental and therapeutic medicine · 2026Article
- The association between androgenic profile and cardiometabolic risk factors in young men: insights from a large observational cohort study.Journal of endocrinological investigation · 2026Article
- Temporal and Regional Trends in Cardiovascular Mortality Associated With Diabetes Mellitus: A Nationwide Analysis From 1999 to 2020 in the United States.Health science reports · 2026Article
- Trends in prevalence of cardiovascular-kidney-metabolic syndrome stages among US young adults, 2011-2020.American heart journal plus : cardiology research and practice · 2026Article
- Burden of atherosclerotic cardiovascular disease attributable to high body mass index, high fasting plasma glucose or high low density lipoprotein cholesterol in young and middle-aged adults from 1990 to 2050.Diabetology & metabolic syndrome · 2026Article
- Review
- Inferior ST-elevation myocardial infarction associated with premature coronary atherosclerosis in a 21-year-old smoker: a case report.European heart journal. Case reports · 2026Article
- Maternal Body Mass Index, Gestational Weight Gain, and Cardiovascular Disease in Offspring.JAMA network open · 2026Article
- Tobacco-Attributable Burden of Early-Onset Ischemic Heart Disease From 1990 to 2023: A Global Analysis Using GBD 2023 and Age-Period-Cohort Modeling.Clinical cardiology · 2026Article
- Age-Dependent Geographic Convergence of Overdose and Cardiovascular Emergency Medical Services Calls: A Spatial Point Process Analysis.Preventing chronic disease · 2026Article
305 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the past 2 decades, a high prevalence of risk factors for cardiovascular disease, such as obesity, physical inactivity, and poor diet, has been observed among young individuals living in developed countries. The rate of substance abuse (opioids, cocaine, electronic cigarettes, and anabolic steroids) is also increasing among young adults, whereas cigarette smoking might be declining. Among younger individuals (aged 18-50 years), the incidence of cardiovascular diseases over the same time period has either been steady or has increased, in contrast to the trend towards a lower incidence of cardiovascular disease in adults aged >50 years. Current observations might, therefore, be used to forecast a potential epidemic of cardiovascular disease in the near future as the younger segment of the population ages. In this Review, we discuss the burden of risk factors for ischaemic heart disease, heart failure, atrial fibrillation, and sudden cardiac death among young adults aged 18-45 years. Furthermore, we discuss the prevalence, incidence, and temporal trends of various cardiovascular diseases among this young segment of the population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.