Evidence map›Paper›PMID 29022286›Full record

GuidelineEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2017

Best clinical practice guidance for local analgesia in paediatric dentistry: an EAPD policy document.

J Kühnisch, M Daubländer, G Klingberg, A Dougall, M Spyridonos Loizides, E Stratigaki, J L Amar, V Anttonen, M Duggal, S Gizani

Abstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Effective anaesthesia when treating teeth affected by molar incisor hypomineralisation (MIH): a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Pooled it
  2. Comparative study of articaine 4% versus lidocaine 2% in the local anesthesia of permanent mandibular first molars affected by MIH: a randomized controlled trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2023
    Trial
  3. Trial
  4. Trial
  5. Article
  6. [Expert consensus on local anesthesia application in pediatric dental therapies].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025
    Article
  7. Swiss paediatric dentists' preferences and experience on the use of articaine and other local/topical anaesthetics.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024
    Article
  8. Article
  9. Self-induced soft-tissue injuries following dental anesthesia in children with and without intellectual disability. A prospective study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 7 countries.

J KühnischDepartment of Operative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians University of Munich, Munich, Germany. jkuehn@dent.med.uni-muenchen.de.
M DaubländerDepartment of Oral Surgery, University Medical Centre Mainz, Mainz, Germany.
G KlingbergDepartment of Pediatric Dentistry, Faculty of Odontology, Malmö University, Malmö, Sweden.
A DougallDepartment of Child and Public Dental Health, Trinity College, Dublin, Republic of Ireland.
M Spyridonos LoizidesPrivate Practice for Paediatric Dentistry, Nicosia, Cyprus.
E StratigakiDepartment of Orthodontics and Paediatric Dentistry, University of Basel, Basel, Switzerland.
J L AmarPrivate Practice for Paediatric Dentistry, Geneva, Switzerland.
V AnttonenResearch Unit of Oral Health Sciences, Department of Cariology, Endodontology and Paediatric Dentistry, University of Oulu, Oulu, Finland.
M DuggalFaculty of Dentistry, National University of Singapore, Singapore, Singapore.
S GizaniDepartment of Paediatric Dentistry, Dental School, National and Kapodistrian University of Athens, Athens, Greece.
Dublin Dental University Hospital · IELudwig-Maximilians-Universität München · DEMalmö University · SENational and Kapodistrian University of Athens · GRNational University of Singapore · SGOulu University Hospital · FIUniversity Medical Center of the Johannes Gutenberg University Mainz · DEUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe European Academy of Paediatric Dentistry (EAPD) proposes this best-practice guidance to help practitioners to decide when and how to use local analgesia to control pain in children, adolescents, and medically compromised individuals during the delivery of oral health care.

methodsA search of different databases was conducted using all terms relevant to the subject. Relevant papers were identified after a review of their titles, abstracts or full papers. Three workshops were held during the corresponding EAPD interim seminar in Torino (Italy) in 2017. Several statements were agreed upon and, furthermore, knowledge gaps were identified.

resultsAn important outcome was that when local analgesia administered appropriately-correct choice of agent(s) and dosage, proper route of administration-it is, firstly, clinically effective for pain-control in treating children and, secondly, it carries a very low risk of morbidity including adverse or side-effects. Furthermore, several gaps in knowledge were identified during the workshop which indicates future research needs. Most importantly it remains unsatisfactory that in several European countries the most frequently used injectable local analgesic agent, articaine, is not approved for usage in children below the age of 4 years.

conclusionWhen considering the dental demand to treat vulnerable (medically compromised) children and adolescents in a safe, painless, less-invasive and effective way, there seems to be an urgent need to close these gaps in knowledge.

Indexed as

Anesthesia, LocalDental Care for ChildrenAdolescentAnesthetics, LocalChildDental Care for Chronically IllDental Care for Persons with DisabilitiesHumansPain ManagementVasoconstrictor AgentsAnesthetics, LocalVasoconstrictor AgentsAdolescentsAdverse eventsChildrenClinical practiceGuidelineLocal analgesiaTechniques of administration

Identifiers

PMID29022286
OpenAlexW2763393495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.