ArticleThe journal of headache and pain2017
The role of α
Article in The journal of headache and pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Myocardial Infarction With Nonobstructive Coronary Arteries: A Significant Adverse Effect of Dihydroergotamine.Cureus · 2025Article
- Dihydroergotamine Increases Histamine Brain Levels and Improves Memory in a Scopolamine-Induced Amnesia Model.International journal of molecular sciences · 2024Article
- New characterization of dihydroergotamine receptor pharmacology in the context of migraine: utilization of a β-arrestin recruitment assay.Frontiers in neurology · 2023Article
- Characterization of the trigeminovascular actions of several adenosine AThe journal of headache and pain · 2018Article
- Dihydroergotamine inhibits the vasodepressor sensory CGRPergic outflow by prejunctional activation of αThe journal of headache and pain · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDihydroergotamine (DHE) is an acute antimigraine agent that displays affinity for dopamine D
methodsFor this purpose, 135 male Wistar rats were pithed and divided into 35 control and 100 pretreated i.v. with ritanserin (100 μg/kg; to exclude the 5-HT
resultsIn control animals (without ritanserin pretreatment), the vasopressor responses to DHE were: (i) unaffected after prazosin (α
conclusionThese results suggest that the DHE-induced vasopressor responses in ritanserin-pretreated pithed rats are mediated by α
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.