Evidence map›Paper›PMID 29022275›Full record

ArticleSports medicine (Auckland, N.Z.)2018

Volume for Muscle Hypertrophy and Health Outcomes: The Most Effective Variable in Resistance Training.

Vandré Casagrande Figueiredo, Belmiro Freitas de Salles, Gabriel S Trajano

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Sports medicine (Auckland, N.Z.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04540367 (Blood Flow Restriction Training for The Shoulder), which is not on this map. Cited by 59 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04540367 nacompletednot on this map

Blood Flow Restriction Training for The Shoulder: A Case for Proximal Benefit

TypeinterventionalSponsorThe Methodist Hospital Research InstituteRan2017 to 2020Enrolled69ConditionsHealthyArmsBlood flow restriction therapy
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 14 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Pooled it
  14. Pooled it
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Vandré Casagrande FigueiredoCenter for Muscle Biology, University of Kentucky, Lexington, KY, USA. v.casagrandefigueiredo@uky.edu.
Belmiro Freitas de SallesPhysical Education Post-Graduation Program, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Gabriel S TrajanoSchool of Exercise and Nutrition Sciences, Institute of Health and Biomedical innovation, Queensland University of Technology, Brisbane, QLD, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistance training is the most effective method to increase muscle mass. It has also been shown to promote many health benefits. Although it is deemed safe and of clinical relevance for treating and preventing a vast number of diseases, a time-efficient and minimal dose of exercise has been the focus of a great number of research studies. Similarly, an inverted U-shaped relationship between training dose/volume and physiological response has been hypothesized to exist. However, the majority of available evidence supports a clear dose-response relationship between resistance training volume and physiological responses, such as muscle hypertrophy and health outcomes. Additionally, there is a paucity of data to support the inverted U-shaped response. Although it may indeed exist, it appears to be much more plastic than previously thought. The overarching principle argued herein is that volume is the most easily modifiable variable that has the most evidenced-based response with important repercussions, be these muscle hypertrophy or health-related outcomes.

Indexed as

ExerciseHumansHypertrophyMuscle FatigueMuscle, SkeletalMuscle StrengthMuscular DiseasesResistance TrainingTime Factors

Identifiers

PMID29022275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.