Evidence map›Paper›PMID 29022248›Full record

ArticleFood and environmental virology2018

Coxsackievirus B4 as a Causative Agent of Diabetes Mellitus Type 1: Is There a Role of Inefficiently Treated Drinking Water and Sewage in Virus Spreading?

Waled M El-Senousy, Adel Abdel-Moneim, Mahmoud Abdel-Latif, Mohamed H El-Hefnawy, Rehab G Khalil

Abstract read
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In one paragraph

Article in Food and environmental virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Association BetweenFrontiers in endocrinology · 2021
    Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. The diabetes pandemic and associated infections: suggestions for clinical microbiology.Reviews in medical microbiology : a journal of the Pathological Society of Great Britain and Ireland · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Waled M El-SenousyEnvironmental Virology Lab, Water Pollution Research Department, National Research Centre (NRC), El Bohouth st., Dokki, Giza, 12622, Egypt. waledmorsy@hotmail.com.ORCID 0000-0003-0649-0728
Adel Abdel-MoneimMolecular Physiology Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni Suef, Egypt.
Mahmoud Abdel-LatifImmunology Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni Suef, Egypt.
Mohamed H El-HefnawyDepartment of Pediatric, National Institute of Diabetes and Endocrinology, Cairo, Egypt.
Rehab G KhalilImmunology Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni Suef, Egypt.
Beni-Suef University · EGNational Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study proposed to detect the enterovirus (EV) infection in children with type 1 diabetes mellitus (T1D) and to assess the role of insufficiently treated water and sewage as sources of viral spreading. Three hundred and eighty-two serum specimens of children with T1D, one hundred serum specimens of children who did not suffer from T1D as control, and forty-eight water and sewage samples were screened for EV RNA using nested RT-PCR. The number of genome copies and infectious units of EVs in raw and treated sewage and water samples were investigated using real-time (RT)-PCR and plaque assay, respectively. T1D markers [Fasting blood glucose (FBG), HbA1c, and C-peptide], in addition to anti-Coxsackie A & B viruses (CVs A & B) IgG, were measured in control, T1D-negative EV (T1D-EV

Indexed as

Enterovirus B, HumanAdolescentBiomarkersChildChild, PreschoolCoxsackievirus InfectionsDiabetes Mellitus, Type 1Drinking WaterFemaleGenome, ViralHumansImmunoglobulin GMaleReal-Time Polymerase Chain ReactionSewageWater PollutionBiomarkersDrinking WaterImmunoglobulin GSewageChildrenCoxsackievirus B4Drinking waterEnterovirusType 1 diabetes

Identifiers

PMID29022248
OpenAlexW2760847656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.