Evidence map›Paper›PMID 29022223›Full record

ReviewJournal of nephrology2017

Acute kidney injury in pregnancy and the role of underlying CKD: a point of view from México.

Margarita Ibarra-Hernández, Oralia Alejandra Orozco-Guillén, María Luz de la Alcantar-Vallín, Ruben Garrido-Roldan, María Patricia Jiménez-Alvarado, Kenia Benitez Castro, Francisco Villa-Villagrana, Mario Borbolla, Juan Manuel Gallardo-Gaona, Guillermo García-García and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Margarita Ibarra-HernándezHospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Jal, Mexico. maribaher@yahoo.es.
Oralia Alejandra Orozco-GuillénInstituto Nacional de Perinatología, México City, Mexico.
María Luz de la Alcantar-VallínHospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Jal, Mexico.
Ruben Garrido-RoldanInstituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
María Patricia Jiménez-AlvaradoHospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Jal, Mexico.
Kenia Benitez CastroHospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Jal, Mexico.
Francisco Villa-VillagranaHospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Jal, Mexico.
Mario BorbollaHospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Jal, Mexico.
Juan Manuel Gallardo-GaonaInstituto Nacional de Perinatología, México City, Mexico.
Guillermo García-GarcíaHospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Jal, Mexico.
Norberto Reyes-ParedesInstituto Nacional de Perinatología, México City, Mexico.
Giorgina Barbara PiccoliCH Le Mans, Le Mans France, University of Torino, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of acute kidney injury in pregnancy (P-AKI) in developed countries is significantly lower than in developing ones, where it is estimated to range between 4 and 26%. Mortality in cases of P-AKI requiring dialysis is high, varying from 20 to 80%. In developing countries, clinical decisions are often based on the availability of services and not on needs. Prenatal surveillance in Mexico does not include serum creatinine, limiting the potential for early diagnosis of AKI and CKD and their differential diagnosis. There are few specialized centers for the care of a pregnancy complicated with kidney disease in Mexico. P-AKI superimposed on preexistent, and usually undiagnosed CKD, is common: in Guadalajara 10 out of the 27 patients with Stage 3-5 CKD or nephrotic proteinuria, that were followed in 2013-2015, required renal replacement therapy (RRT) in pregnancy; in the same period in Mexico City out of 18 patients with P-AKI requiring dialysis, 5 remained dialysis dependent, 3 started dialysis in the following year after their pregnancy and only 1 fully recovered renal function. The grim prognosis is exacerbated by the fact that 70% of Mexicans are not reimbursed for dialysis, and pregnancy-related coverage lasts for only 42 days after delivery. Perinatal results are no less troubling, as most patients with P-AKI give birth preterm to small or very small babies. While our data do not allow us to evaluate needs, they do make it possible to define the complexity of the problems faced in the care of P-AKI in Mexico. Early diagnosis of P-AKI and chronic kidney disease (CKD) is needed to protect mothers and children and the country urgently needs programs to enable it to fulfil the World Health Organization's imperative that we "make every mother and child count".

Indexed as

Acute Kidney InjuryAdultFemaleHumansMexicoPregnancyPregnancy ComplicationsRenal Insufficiency, ChronicRenal Replacement TherapyAcute kidney injuryChronic kidney diseaseMéxicoPregnancy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.