Evidence map›Paper›PMID 29022183›Full record

ArticleEnvironmental science and pollution research international2018

In search of a comprehensible set of endpoints for the routine monitoring of neurotoxicity in vertebrates: sensory perception and nerve transmission in zebrafish (Danio rerio) embryos.

Daniel Stengel, Sarah Wahby, Thomas Braunbeck

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Impacts of isopyrazam exposure on the development of early-life zebrafish (Danio rerio).Environmental science and pollution research international · 2018
    Article
  11. Article
  12. An ecotoxicological view on neurotoxicity assessment.Environmental sciences Europe · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Daniel StengelAquatic Ecology and Toxicology Group, Center for Organismal Studies (COS), University of Heidelberg, Im Neuenheimer Feld 120, 69120, Heidelberg, Germany.
Sarah WahbyAquatic Ecology and Toxicology Group, Center for Organismal Studies (COS), University of Heidelberg, Im Neuenheimer Feld 120, 69120, Heidelberg, Germany.
Thomas BraunbeckAquatic Ecology and Toxicology Group, Center for Organismal Studies (COS), University of Heidelberg, Im Neuenheimer Feld 120, 69120, Heidelberg, Germany. braunbeck@uni-hd.de.ORCID http://orcid.org/0000-0002-1785-6759
Heidelberg University · DE

Funding

BMBF 02WRS1282G
6 · The paper itself

Abstract

In order to develop a test battery based on a variety of neurological systems in fish, three sensory systems (vision, olfaction, and lateral line) as well as nerve transmission (acetylcholine esterase) were analyzed in zebrafish (Danio rerio) embryos with respect to their suitability as a model for the screening of neurotoxic trace substances in aquatic ecosystems. As a selection of known or putative neurotoxic compounds, amidotrizoic acid, caffeine, cypermethrin, dichlorvos, 2,4-dinitrotoluene, 2,4-dichlorophenol, 4-nonylphenol, perfluorooctanoic acid, and perfluorooctane sulfonic acid were tested in the fish embryo test (OECD test guideline 236) to determine EC

Indexed as

AcetylcholinesteraseAnimalsEmbryo, NonmammalianFish ProteinsLateral Line SystemNeurotoxinsOlfactory PerceptionSynaptic TransmissionToxicity TestsVisual PerceptionWater Pollutants, ChemicalZebrafishAcetylcholinesteraseFish ProteinsNeurotoxinsWater Pollutants, ChemicalAcetylcholinesteraseFish embryo testHRIV conceptNeuromastsNeurotoxicityOlfactionOtotoxicityRetinaVisionZebrafish

Identifiers

PMID29022183
OpenAlexW2761133614

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.