Evidence map›Paper›PMID 29022150›Full record

ArticleTechniques in coloproctology2017

Healing of the perineal wound after proctectomy in Crohn's disease patients: only preoperative perineal sepsis predicts poor outcome.

W Li, L Stocchi, F Elagili, R P Kiran, S A Strong

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Techniques in coloproctology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Long-term perineal wound healing and re-operation rates after proctectomy in patients with inflammatory bowel disease-A retrospective multicentre study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Article
  3. Review
  4. How to Approach the Difficult Perineum in Crohn's Disease.Clinics in colon and rectal surgery · 2025
    Review
  5. Persistent perineal sinus following proctocolectomy in the inflammatory bowel disease patient.JGH open : an open access journal of gastroenterology and hepatology · 2023
    Review
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

W LiDepartment of Gastrointestinal Surgery, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
L StocchiDepartment of Colorectal Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.
F ElagiliDepartment of Colorectal Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.
R P KiranDivision of Colorectal Surgery, Columbia University Medical Center, New York Presbyterian Hospital, New York, NY, USA.
S A StrongDivision of Gastrointestinal Surgery, Digestive Health Center, 676 North Saint Clair Street, Suite 650, Chicago, IL, 60611, USA. sstrong2@nm.org.
Cleveland Clinic · USGuangzhou Medical University · CNNewYork–Presbyterian Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of our study was to assess perineal wound healing in patients with Crohn's disease (CD) who undergo proctectomy or proctocolectomy with end ileostomy and to evaluate the influence of various factors including types of perineal dissection on eventual wound healing.

methodsData for patients with CD who underwent proctectomy or total proctocolectomy with end ileostomy from 1995 to 2012 were reviewed. The relationship between perineal wound healing and demographics, patient characteristics, and other factors was assessed using univariate and multivariate analyses.

resultsThe perineal wound healed by 12 weeks in 72 (52.9%) out of 136 patients (63.2% female, mean age 41 ± 13 years); delayed healing occurred in 35 patients (25.7%), and in 29 patients (21.3%), there was non-healing. On multivariate analysis, the only factor associated with delayed healing and non-healing was preoperative perineal sepsis (p = 0.001).

conclusionsAfter proctectomy or proctocolectomy for CD, perineal wound healing is poor and poses a particular challenge for patients with preoperative perineal sepsis. These findings support a preoperative discussion regarding CD patients that examines potential outcomes and the consideration of measures such as the initial creation of defunctioning ostomy or control/drainage of local sepsis prior to proctectomy.

Indexed as

AdultCrohn DiseaseFemaleHumansMaleMiddle AgedMultivariate AnalysisPerineumPostoperative ComplicationsPreoperative PeriodProctocolectomy, RestorativeRetrospective StudiesRisk FactorsSepsisTreatment OutcomeWound HealingCrohn’s diseaseHealingPerineal woundProctectomyProctocolectomy

Identifiers

PMID29022150
OpenAlexW2764000234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.