Evidence map›Paper›PMID 29022112›Full record

Observational studyJapanese journal of ophthalmology2018

The use of zonal analysis of peripapillary choroidal thickness in primary open-angle glaucoma.

Luis Emilio Pablo, Maria Pilar Bambo, Beatriz Cameo, Blanca Ferrández, Noemí Güerri, Vicente Polo, Jose Manuel Larrosa, Javier Moreno-Montañés, Elena Garcia-Martin

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Japanese journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luis Emilio PabloOphthalmology Department, Miguel Servet University Hospital, C/Padre Arrupe, Consultas Externas de Oftalmología, 50009, Saragossa, Spain.
Maria Pilar BamboOphthalmology Department, Miguel Servet University Hospital, C/Padre Arrupe, Consultas Externas de Oftalmología, 50009, Saragossa, Spain. mpbamborubio@gmail.com.
Beatriz CameoOphthalmology Department, Miguel Servet University Hospital, C/Padre Arrupe, Consultas Externas de Oftalmología, 50009, Saragossa, Spain.
Blanca FerrándezOphthalmology Department, Miguel Servet University Hospital, C/Padre Arrupe, Consultas Externas de Oftalmología, 50009, Saragossa, Spain.
Noemí GüerriOphthalmology Department, Miguel Servet University Hospital, C/Padre Arrupe, Consultas Externas de Oftalmología, 50009, Saragossa, Spain.
Vicente PoloOphthalmology Department, Miguel Servet University Hospital, C/Padre Arrupe, Consultas Externas de Oftalmología, 50009, Saragossa, Spain.
Jose Manuel LarrosaOphthalmology Department, Miguel Servet University Hospital, C/Padre Arrupe, Consultas Externas de Oftalmología, 50009, Saragossa, Spain.
Javier Moreno-MontañésDepartment of Ophthalmology, Clínica Universidad de Navarra, Pamplona, Spain.
Elena Garcia-MartinOphthalmology Department, Miguel Servet University Hospital, C/Padre Arrupe, Consultas Externas de Oftalmología, 50009, Saragossa, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate automatic peripapillary choroidal thickness (PPCT) measurements in a wide area around the optic disc and various established zones in primary open-angle glaucoma (POAG) patients and age- and sex-matched healthy controls using a new swept-source optical coherence tomography (SS-OCT) device. STUDY

designSingle center cross-sectional observational study.

methodsA total of 135 POAG patients and 86 healthy subjects were consecutively enrolled. An optic disc 6.0 × 6.0 mm three-dimensional scan OD was obtained using the SS-OCT Triton. A 26 × 26 cube-grid centered in the optic disc was generated to automatically measure choroidal thickness. Seven choroidal zones were established (superior temporal, central, and nasal; inferior temporal, central, and nasal, and the optic nerve head) and compared between healthy controls and POAG patients.

resultsPPCT was significantly thinner in the central superior, nasal superior, and nasal inferior zones of the POAG subjects. Choroidal thickness in the central superior zone was 124.61 ± 54.95 µm in POAG group vs 156.17 ± 80.89 µm in healthy controls (p = 0.029); in the nasal superior zone, 133.84 ± 58.89 µm in the POAG group vs 168.34 ± 73.45 µm in healthy controls (p = 0.012); and in the nasal inferior zone, 113.45 ± 49.93 µm in the POAG group vs 137.47 ± 65.96 µm in healthy controls (p = 0.049).

conclusionCompared with healthy subjects, glaucoma patients present with peripapillary choroidal thinning, especially in the central superior, nasal superior, and nasal inferior zones. The new SS-OCT could be a useful tool to evaluate choroidal thinning, and it could be an additional support to facilitate glaucoma diagnosis.

Indexed as

AgedAged, 80 and overChoroidCross-Sectional StudiesFemaleGlaucoma, Open-AngleHealthy VolunteersHumansIntraocular PressureMaleMiddle AgedOptic DiskTomography, Optical CoherenceTonometry, OcularVisual FieldsVisual Field TestsChoroidOptical coherence tomographyPeripapillary choroidal thicknessPrimary open-angle glaucoma

Identifiers

PMID29022112

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.