Evidence map›Paper›PMID 29021993›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2018

Multisite concordance of apparent diffusion coefficient measurements across the NCI Quantitative Imaging Network.

David C Newitt, Dariya Malyarenko, Thomas L Chenevert, C Chad Quarles, Laura Bell, Andriy Fedorov, Fiona Fennessy, Michael A Jacobs, Meiyappan Solaiyappan, Stefanie Hectors and 19 more

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Additive value of diffusion-weighted MRI in the I-SPY 2 TRIAL.Journal of magnetic resonance imaging : JMRI · 2019
    Trial
  3. Multi-parametric MRI radiomics to predict sensitivity to neoadjuvant chemoradiotherapy based on multi-regions of interest in locally advanced rectal cancer: a multicenter study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
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  13. Review
  14. Quantitative Imaging Informatics for Cancer Research.JCO clinical cancer informatics · 2020
    Article
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

David C NewittUniversity of California San Francisco, Department of Radiology and Biomedical Imaging, San Francisco, California, United States.
Dariya MalyarenkoUniversity of Michigan, Department of Radiology, Ann Arbor, Michigan, United States.
Thomas L ChenevertUniversity of Michigan, Department of Radiology, Ann Arbor, Michigan, United States.
C Chad QuarlesBarrow Neurological Institute, Division of Imaging Research, Phoenix, Arizona, United States.
Laura BellBarrow Neurological Institute, Division of Imaging Research, Phoenix, Arizona, United States.
Andriy FedorovHarvard Medical School, Brigham and Women's Hospital, Department of Radiology, Boston, Massachusetts, United States.
Fiona FennessyHarvard Medical School, Brigham and Women's Hospital, Department of Radiology, Boston, Massachusetts, United States.
Michael A JacobsThe Johns Hopkins School of Medicine, Russell H. Morgan Department of Radiology and Radiological Science and Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, United States.
Meiyappan SolaiyappanThe Johns Hopkins School of Medicine, Russell H. Morgan Department of Radiology and Radiological Science and Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, United States.
Stefanie HectorsTranslational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, United States.
Bachir TaouliTranslational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, United States.
Mark MuziUniversity of Washington, Department of Radiology, Neurology, and Radiation Oncology, Seattle, Washington, United States.
Paul E KinahanUniversity of Washington, Department of Radiology, Neurology, and Radiation Oncology, Seattle, Washington, United States.
Kathleen M SchmaindaMedical College of Wisconsin, Department of Radiology, Milwaukee, Wisconsin, United States.
Melissa A PrahMedical College of Wisconsin, Department of Radiology, Milwaukee, Wisconsin, United States.
Erin N TaberOregon Health and Science University, Advanced Imaging Research Center, Portland, Oregon, United States.
Christopher KroenkeOregon Health and Science University, Advanced Imaging Research Center, Portland, Oregon, United States.
Wei HuangOregon Health and Science University, Advanced Imaging Research Center, Portland, Oregon, United States.
Lori R ArlinghausVanderbilt University Medical Center, Vanderbilt University Institute of Imaging Science, Nashville, Tennessee, United States.
Thomas E YankeelovThe University of Texas at Austin, Institute for Computational and Engineering Sciences, Department of Biomedical Engineering and Diagnostic Medicine, Austin, Texas, United States.
Yue CaoUniversity of Michigan, Radiation Oncology, Radiology, and Biomedical Engineering, Ann Arbor, Michigan, United States.
Madhava AryalUniversity of Michigan, Radiation Oncology, Radiology, and Biomedical Engineering, Ann Arbor, Michigan, United States.
Yi-Fen YenHarvard Medical School, Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Charlestown, Massachusetts, United States.
Jayashree Kalpathy-CramerHarvard Medical School, Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Charlestown, Massachusetts, United States.
Amita Shukla-DaveMemorial Sloan-Kettering Cancer Center, Department of Medical Physics and Radiology, New York, New York, United States.
Maggie FungMemorial Sloan-Kettering Cancer Center, GE Healthcare, New York, New York, United States.
Jiachao LiangHologic Inc., Sunnyvale, California, United States.
Michael BossNational Institute of Standards and Technology, Applied Physics Division, Boulder, Colorado, United States.
Nola HyltonUniversity of California San Francisco, Department of Radiology and Biomedical Imaging, San Francisco, California, United States.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
ARRA - ADOPT New Technologies for RDC/CDMSU01CA080098 · NCI · AMERICAN COLLEGE OF RADIOLOGY · PI SCHNALL, MITCHELL D. · 1999 to 2011
$182.7M
BIOSTATISTICS DATA MANAGEMENT CENTER FOR ACROINU01CA079778 · NCI · BROWN UNIVERSITY · PI GATSONIS, CONSTANTINE A. · 1999 to 2011
$48.6M
Image Guided Therapy Center - Ultrasound-based sensor system for the monitoring of COVID-19 patientsP41EB015898 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI TEMPANY, CLARE M · 2012 to 2021
$18.9M
Elimination of Instrumental Bias for Quantitative Diffusion Imaging in Clinical Oncology TrialsR01CA190299 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MALYARENKO, DARIYA I. · 2015 to 2025
$6.4M
Multi-Modality Quantitiative Imaging for Evaluation of Response to Cancer TherapyU01CA140204 · NCI · JOHNS HOPKINS UNIVERSITY · PI DU, YONG, SOLNES, LILJA · 2011 to 2022
$6.1M
Advanced PET/CT Imaging for Improving Clinical TrialsU01CA148131 · NCI · UNIVERSITY OF WASHINGTON · PI KINAHAN, PAUL E., LINDEN, HANNAH M · 2010 to 2019
$6.0M
MRI CONTRAST AGENT METHODS TO ASSESS TUMOR ANGIOGENESISR01CA082500 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI SCHMAINDA, KATHLEEN MARIE · 2000 to 2016
$5.0M
Quantitative (Perfusion and Diffusion) MRI Biomarkers to Measure Glioma ResponseU01CA176110 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI SCHMAINDA, KATHLEEN MARIE · 2014 to 2023
$4.9M
Real-time In Vivo MRI Biomarkers for Breast Cancer Pre-Operative Treatment TrialsR01CA132870 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HYLTON-WATSON, NOLA M., NEWITT, DAVID C · 2008 to 2019
$4.8M
Quantitative MRI for Predicting Response of Breast Cancer to Neoadjuvant TherapyU01CA142565 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KARCZMAR, GREGORY S., NANDA, RITA · 2010 to 2019
$4.5M
NCI NIH HHS P30 CA006973NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA082500NCI NIH HHS R01 CA132870NCI NIH HHS R01 CA158079NCI NIH HHS R01 CA190299NCI NIH HHS R50 CA211270NCI NIH HHS U01 CA079778NCI NIH HHS U01 CA080098NCI NIH HHS U01 CA140204NCI NIH HHS U01 CA142565NCI NIH HHS U01 CA148131NCI NIH HHS U01 CA151235NCI NIH HHS U01 CA151261NCI NIH HHS U01 CA154601NCI NIH HHS U01 CA154602NCI NIH HHS U01 CA166104NCI NIH HHS U01 CA172320NCI NIH HHS U01 CA176110NCI NIH HHS U01 CA183848NCI NIH HHS U01 CA190254NCI NIH HHS U01 CA211205NCI NIH HHS U01 CA225427NCI NIH HHS U24 CA180918NCI NIH HHS U24 CA180927NIBIB NIH HHS P41 EB015898
6 · The paper itself

Abstract

Diffusion weighted MRI has become ubiquitous in many areas of medicine, including cancer diagnosis and treatment response monitoring. Reproducibility of diffusion metrics is essential for their acceptance as quantitative biomarkers in these areas. We examined the variability in the apparent diffusion coefficient (ADC) obtained from both postprocessing software implementations utilized by the NCI Quantitative Imaging Network and online scan time-generated ADC maps. Phantom and

Indexed as

apparent diffusion coefficientbreast MRIreproducibility

Identifiers

PMID29021993
PMCPMC5633866

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.