Evidence map›Paper›PMID 29021992›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2017

Classifying symmetrical differences and temporal change for the detection of malignant masses in mammography using deep neural networks.

Thijs Kooi, Nico Karssemeijer

Open access · greenAbstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 58 citations in OpenAlex.

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  9. Artificial Intelligence in Breast X-Ray Imaging.Seminars in ultrasound, CT, and MR · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Thijs KooiRadboudUMC Nijmegen, Diagnostic Image Analysis Group, Department of Radiology and Nuclear Medicine, Nijmegen, The Netherlands.
Nico KarssemeijerRadboudUMC Nijmegen, Diagnostic Image Analysis Group, Department of Radiology and Nuclear Medicine, Nijmegen, The Netherlands.
Analysis Group (United States) · USRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigate the addition of symmetry and temporal context information to a deep convolutional neural network (CNN) with the purpose of detecting malignant soft tissue lesions in mammography. We employ a simple linear mapping that takes the location of a mass candidate and maps it to either the contralateral or prior mammogram, and regions of interest (ROIs) are extracted around each location. Two different architectures are subsequently explored: (1) a fusion model employing two datastreams where both ROIs are fed to the network during training and testing and (2) a stagewise approach where a single ROI CNN is trained on the primary image and subsequently used as a feature extractor for both primary and contralateral or prior ROIs. A "shallow" gradient boosted tree classifier is then trained on the concatenation of these features and used to classify the joint representation. The baseline yielded an AUC of 0.87 with confidence interval [0.853, 0.893]. For the analysis of symmetrical differences, the first architecture where both primary and contralateral patches are presented during training obtained an AUC of 0.895 with confidence interval [0.877, 0.913], and the second architecture where a new classifier is retrained on the concatenation an AUC of 0.88 with confidence interval [0.859, 0.9]. We found a significant difference between the first architecture and the baseline at high specificity with [Formula: see text]. When using the same architectures to analyze temporal change, we yielded an AUC of 0.884 with confidence interval [0.865, 0.902] for the first architecture and an AUC of 0.879 with confidence interval [0.858, 0.898] in the second setting. Although improvements for temporal analysis were consistent, they were not found to be significant. The results show our proposed method is promising and we suspect performance can greatly be improved when more temporal data become available.

Indexed as

breast cancercomputer-aided diagnosisconvolutional neural networksdeep learningmachine learning

Identifiers

PMID29021992
PMCPMC5633751
OpenAlexW2761969486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.