Evidence map›Paper›PMID 29021851›Full record

ArticleJournal of arrhythmia2017

Cardiac troponin T as a predictor of cardiac death in patients with left ventricular dysfunction.

Hironori Nakamura, Shinichi Niwano, Hidehira Fukaya, Masami Murakami, Jun Kishihara, Akira Satoh, Tomoharu Yoshizawa, Jun Oikawa, Naruya Ishizue, Tazuru Igarashi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of arrhythmia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Hironori NakamuraDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Shinichi NiwanoDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Hidehira FukayaDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Masami MurakamiDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Jun KishiharaDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Akira SatohDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Tomoharu YoshizawaDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Jun OikawaDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Naruya IshizueDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Tazuru IgarashiDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Tamami FujiishiDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Junya AkoDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Kitasato University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac troponin T (cTnT) has been reported to be associated with cardiac mortality. In the present study, we evaluated the role of routine assessment of cTnT as a predictor of future cardiac death in patients with left ventricular (LV) dysfunction.

methodsPatients who were eligible for prophylactic implantable cardioverter defibrillator (ICD) were included from cardiac catheterization database. Inclusion criteria were patients with LV ejection fraction of ≤ 35% and with New York Heart Association (NYHA) ≥class II. Exclusion criteria were patients with acute coronary syndrome, ICD for secondary prevention, NYHA class IV, and lack of data. The final study patients were divided into the following three groups in accordance with two quartile points of serum cTnT levels: low cTnT, intermediate cTnT, and high cTnT groups. The primary endpoint of this study was cardiac death.

resultsA total of 70 patients were included (mean age, 62±13 years; male individuals, 56; ischemic, 36; and non-ischemic, 34). During the observation period of 2.2 years, cardiac death was observed in 17 patients (fatal arrhythmic event, 9; heart failure, 7; myocardial infarction, 1). In the Kaplan-Meier analysis, the high cTnT group showed the highest risk among all the groups (

conclusionThe cTnT levels in a stable state were associated with cardiac death in patients with LV dysfunction, even in those with non-ischemic diseases.

Indexed as

Cardiac deathCardiac troponin TLeft ventricular dysfunctionSudden death

Identifiers

PMID29021851
PMCPMC5634714
OpenAlexW2751365990

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.