Evidence map›Paper›PMID 29021720›Full record

ArticleAnnals of burns and fire disasters2017

Burn injury: review of pathophysiology and therapeutic modalities in major burns.

I Kaddoura, G Abu-Sittah, A Ibrahim, R Karamanoukian, N Papazian

Abstract read
In one paragraph

Article in Annals of burns and fire disasters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Spray Gel Extract of Karsen LeavesAnnals of burns and fire disasters · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. MicroRNA Profiles in Critically Ill Patients.Current medicinal chemistry · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Acellular fish skin for wound healing.International wound journal · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Stem cell-based therapy for human diseases.Signal transduction and targeted therapy · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

I KaddouraDivision of Plastic & Reconstructive Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
G Abu-SittahDivision of Plastic & Reconstructive Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
A IbrahimDivision of Plastic & Reconstructive Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
R KaramanoukianPlastic & Reconstructive Surgery, Kare Plastic Surgery & Skin Health Center, Santa Monica, California, USA.
N PapazianDivision of Plastic & Reconstructive Surgery, American University of Beirut Medical Center, Beirut, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite a considerable decrease in their incidence worldwide, burn injuries remain one of the commonest forms of trauma and account for a weighty proportion of trauma cases in health-care emergencies around the globe. Although the latest data reveal a substantial decline in burn-related mortality and hospital admissions in the US over the past three decades, severe thermal injuries continue to trigger devastating morbidity and significant mortality while their management remains a dynamic challenge for the entire medical and paramedical community. Concrete evidence continues to be established regarding burn-associated pathophysiologic responses, and their destructive sequelae and deleterious effects in survivors at cellular, systemic as well as socio-economic level. Better understanding of these responses have contributed to advances in therapeutic strategies, improved long-term outcomes and catalyzed the reintegration of victims back into society. This paper describes the current understanding of the pathophysiology of a burn injury and characterizes both local and systemic pathophysiologic responses in terms of metabolic, hemodynamics, cardiac, renal, hepatic, gastro-intestinal, immunologic, endocrine as well as male reproductive systems in an attempt to understand the corresponding treatment modalities for this unique patient population.

Indexed as

burn injurymajor burnsmodulatorspathophysiology

Identifiers

PMID29021720
PMCPMC5627559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.