Evidence map›Paper›PMID 29021642›Full record

ArticleColombia medica (Cali, Colombia)2017

Bevacizumab as a treatment for hereditary hemorrhagic telangiectasia in children: a case report.

Fabio E Ospina, Alex Echeverri, Iván Posso-Osorio, Lina Jaimes, Jaiber Gutierrez, Gabriel J Tobón

Open access · greenAbstract readCase Reports
In one paragraph

Article in Colombia medica (Cali, Colombia), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fabio E OspinaInstituto de Investigaciones Clínicas, Fundación Valle del Lili, Cali, Colombia.
Alex EcheverriGrupo de Investigación en Reumatología, Autoinmunidad y Medicina Traslacional (GIRAT) Departamento de Reumatologia, Fundación Valle del Lili, Cali, Colombia.
Iván Posso-OsorioInstituto de Investigaciones Clínicas, Fundación Valle del Lili, Cali, Colombia.
Lina JaimesDepartamento de Pediatria, Fundación Valle del Lili, Cali, Colombia.
Jaiber GutierrezDepartamento de Pediatria, Fundación Valle del Lili, Cali, Colombia.
Gabriel J TobónGrupo de Investigación en Reumatología, Autoinmunidad y Medicina Traslacional (GIRAT) Departamento de Reumatologia, Fundación Valle del Lili, Cali, Colombia.
Fundación Valle del Lili · COIcesi University · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

case descriptionFive-year-old female patient with hereditary hemorrhagic telangiectasia. CLINICAL

findingsDeterioration of cardiopulmonary function with higher oxygen requirements secondary to pulmonary arteriovenous shunts, epistaxis. TREATMENT AND OUTCOME: The patient was treated with the monoclonal antibody bevacizumab, which inhibits the vascular endothelial growth factor, with good clinical outcome. CLINICAL RELEVANCE: Hereditary hemorrhagic telangiectasia is an autosomal dominant disorder characterized by arteriovenous malformations in different organs, making its clinical presentations varied. Systemic therapeutic options for a generalized disease are limited. The monoclonal antibody bevacizumab, seems to be a good option in this disorder. Although reported as successful in adult population, its use in pediatric population has not yet been reported. Here we report the use of bevacizumab in a 5-year-old female patient with hereditary hemorrhagic telangiectasia, showing clinical benefits and good outcome.

Indexed as

Angiogenesis InhibitorsBevacizumabChild, PreschoolFemaleHumansTelangiectasia, Hereditary HemorrhagicTreatment OutcomeVascular Endothelial Growth Factor AAngiogenesis InhibitorsBevacizumabVascular Endothelial Growth Factor ABevacizumabOsler-Rendu-Weber DiseasePediatricsTelangiectasia Hereditary Hemorrhagic

Identifiers

PMID29021642
PMCPMC5625558
OpenAlexW2735132959

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.