Evidence map›Paper›PMID 29021588›Full record

ArticleScientific reports2017

Robust Fusion of Diffusion MRI Data for Template Construction.

Zhanlong Yang, Geng Chen, Dinggang Shen, Pew-Thian Yap

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhanlong YangSchool of Marine Science and Technology, Northwestern Polytechnical University, Xi'an, 710072, China.
Geng ChenDepartment of Radiology and Biomedical Research Imaging Center (BRIC), University of North Carolina at Chapel Hill, NC, 27599, USA.
Dinggang ShenDepartment of Radiology and Biomedical Research Imaging Center (BRIC), University of North Carolina at Chapel Hill, NC, 27599, USA. dgshen@med.unc.edu.
Pew-Thian YapDepartment of Radiology and Biomedical Research Imaging Center (BRIC), University of North Carolina at Chapel Hill, NC, 27599, USA. ptyap@med.unc.edu.

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
NEUROIMAGING OF CONNECTIVITY IN ALCOHOLISMR01AA012388 · NIAAA · SRI INTERNATIONAL · PI PFEFFERBAUM, ADOLF, SULLIVAN, EDITH VIONI · 2000 to 2015
$10.6M
Development of Robust Brain Measurement Tools Informed by Ultrahigh Field 7T MRIR01EB006733 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2008 to 2020
$4.5M
Quantifying Brain Abnormality by Multimodality Neuroimage Analysis,R01AG041721 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, MINGXIA · 2012 to 2019
$3.0M
Infant Brain Measurement and Super-Resolution Atlas ConstructionR01MH100217 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SHEN, DINGGANG · 2013 to 2016
$2.3M
Fast, Robust Analysis of Large Population DataR01EB009634 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SHEN, DINGGANG · 2011 to 2014
$1.3M
Diagnosis of Alzheimer's Disease Using Dynamic High-Order Brain NetworksR01EB022880 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2018
$1.1M
Robust White Matter Morphometry with Small DatabasesR01NS093842 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2018
$1.1M
NIAAA NIH HHS R01 AA012388NIA NIH HHS R01 AG041721NIBIB NIH HHS R01 EB006733NIBIB NIH HHS R01 EB009634NIBIB NIH HHS R01 EB022880NIMH NIH HHS R01 MH100217NIMH NIH HHS U54 MH091657NINDS NIH HHS R01 NS093842
6 · The paper itself

Abstract

Construction of brain templates is generally carried out using a two-step procedure involving registering a population of images to a common space and then fusing the aligned images to form a template. In practice, image registration is not perfect and simple averaging of the images will blur structures and cause artifacts. In diffusion MRI, this is further complicated by intra-voxel inter-subject differences in fiber orientation, fiber configuration, anisotropy, and diffusivity. In this paper, we propose a method to improve the construction of diffusion MRI templates in light of inter-subject differences. Our method involves a novel q-space (i.e., wavevector space) patch matching mechanism that is incorporated in a mean shift algorithm to seek the most probable signal at each point in q-space. Our method relies on the fact that the mean shift algorithm is a mode seeking algorithm that converges to the mode of a distribution and is hence robust to outliers. Our method is therefore in effect seeking the most probable signal profile at each voxel given a distribution of signal profiles. Experimental results show that our method yields diffusion MRI templates with cleaner fiber orientations and less artifacts caused by inter-subject differences in fiber orientation.

Indexed as

Diffusion Magnetic Resonance ImagingImage Processing, Computer-AssistedAlgorithmsComputer SimulationDatabases as TopicHumansProbabilitySignal-To-Noise Ratio

Identifiers

PMID29021588
PMCPMC5636808

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.