Evidence map›Paper›PMID 29021476›Full record

ArticleInternal medicine (Tokyo, Japan)2017

A Rare Monocytic Crisis of Chronic Myelogenous Leukemia Presenting with Unusual Extramedullary Manifestations and an Atypical (14;22)(q24;q11.2) Translocation in the Bone Marrow.

Morihiro Inoue, Masao Hagihara, Tomoyuki Uchida, Jian Hua, Takeshi Nakajima, Shogo Tajima, Yasunori Ota

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Chronic myeloid leukemia with a significant increase of monocytes and rare karyotype: A case report and literature review.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Morihiro InoueDepatment of Hematology, Eiju General Hospital, Japan.
Masao HagiharaDepatment of Hematology, Eiju General Hospital, Japan.
Tomoyuki UchidaDepatment of Hematology, Eiju General Hospital, Japan.
Jian HuaDepatment of Hematology, Eiju General Hospital, Japan.
Takeshi NakajimaDepartment of Opthalmology, Eiju General Hospital, Japan.
Shogo TajimaDepartment of Pathology, Eiju General Hospital, Japan.
Yasunori OtaDepartment of Pathology, Teikyo University School of Medicine, Japan.
Eiju General Hospital · JPTeikyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 48-year-old man was admitted due to marked leukocytosis. Bone marrow examinations resulted in a diagnosis of Philadelphia (Ph) chromosome-positive chronic myeloid leukemia. One month later, massive muscle and bone invasion by leukemic cells was detected. After induction chemotherapy, he complained of a headache and visual loss, which was caused by a leukemic infiltration in the central nervous system. After temporary remission in response to chemotherapy, the disease relapsed in the form of an intracranial tumor. The unusual t(14;22)(q24;q11.2) translocation of the Ph-chromosome and the significant increase in monocytes observed might have contributed to the unique and aggressive clinical course.

Indexed as

Blast CrisisBone Marrow NeoplasmsCentral Nervous System NeoplasmsHumansLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMaleMiddle AgedMonocytesPhiladelphia ChromosomeTranslocation, Genetic(14;22)(q24;q11.2) translocationextramedullary manifestationsmonocytic crisisPhiladelphia (Ph) chromosome positive chronic myelogenous leukemia

Identifiers

PMID29021476
PMCPMC5790724
OpenAlexW2762390473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.