Evidence map›Paper›PMID 29021465›Full record

ArticleInternal medicine (Tokyo, Japan)2017

Insulinoma with a History of Epilepsy: Still a Possible Misleading Factor in the Early Diagnosis of Insulinoma.

Takaaki Murakami, Takafumi Yamashita, Daisuke Yabe, Toshihiko Masui, Yuki Teramoto, Sachiko Minamiguchi, Keisho Hirota, Masahito Ogura, Kazuaki Nagashima, Nobuya Inagaki

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Frontiers in endocrinology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Takaaki MurakamiDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Takafumi YamashitaDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Daisuke YabeDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Toshihiko MasuiDepartment of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kyoto University Graduate School of Medicine, Japan.
Yuki TeramotoDepartment of Diagnostic Pathology, Kyoto University Graduate School of Medicine, Japan.
Sachiko MinamiguchiDepartment of Diagnostic Pathology, Kyoto University Graduate School of Medicine, Japan.
Keisho HirotaDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Masahito OguraDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Kazuaki NagashimaDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Nobuya InagakiDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A delayed diagnosis of insulinoma remains a clinical issue. Hypoglycemic symptoms can mimic neuropsychiatric disorders such as epilepsy. A 27-year-old woman with a history of epilepsy and anti-epileptic drugs (AEDs) developed repeated seizures and neuropsychiatric symptoms after a 9-year asymptomatic interval. She had received transient treatment with AEDs before the possibility of hypoglycemia was considered. Following a clinical diagnosis of insulinoma, distal pancreatectomy was performed; her seizures didn't occur again. The early diagnosis of insulinoma requires vigilance not only for hypoglycemia in patients with neuropsychiatric symptoms but also for the possible masking effects of a history of epilepsy and preceding AED usage.

Indexed as

Delayed DiagnosisAdultEarly DiagnosisEpilepsies, PartialFemaleHumansInsulinomaPancreatectomyPancreatic NeoplasmsTreatment Outcomeanti-epileptic drugcontinuous glucose monitoringepilepsyhypoglycemiainsulinomamisdiagnosis

Identifiers

PMID29021465
PMCPMC5742393

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.