Evidence map›Paper›PMID 29021430›Full record

ArticleInternal medicine (Tokyo, Japan)2017

Crizotinib-induced Rectal Perforation with Abscess.

Asako Yanagisawa, Noriko Hayama, Hiroyuki Amano, Makoto Nakamura, Satoshi Hirano, Sukeyuki Nakamura, Hiroshi Tabeta

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Asako YanagisawaDepartment of Respiratory Medicine, Funabashi Municipal Medical Center, Japan.
Noriko HayamaDepartment of Respiratory Medicine, Funabashi Municipal Medical Center, Japan.
Hiroyuki AmanoDepartment of Respiratory Medicine, Funabashi Municipal Medical Center, Japan.
Makoto NakamuraDepartment of Respiratory Medicine, Funabashi Municipal Medical Center, Japan.
Satoshi HiranoDepartment of Oncology Medicine, Funabashi Municipal Medical Center, Japan.
Sukeyuki NakamuraDepartment of Respiratory Medicine, Funabashi Municipal Medical Center, Japan.
Hiroshi TabetaDepartment of Respiratory Medicine, Funabashi Municipal Medical Center, Japan.
Funabashi Municipal Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 86-year-old Japanese man was diagnosed with stage IV lung adenocarcinoma. The patient was treated with crizotinib after echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) rearrangement was detected from his pleural effusion. He subsequently developed abdominal pain and rebound tenderness in the right lower abdomen. Contrast-enhanced abdominal CT showed a low-density area in the abdominal cavity. The size of the abscess was decreased by drainage and the administration of antibiotics. Fistulography revealed a fistula from the rectum to the abscess, and a diagnosis of lower intestinal tract perforation with abscess formation was made. Crizotinib was discontinued and treatment with alectinib was initiated. The patient remains under treatment as an outpatient at our department without adverse effects.

Indexed as

AbscessAdenocarcinomaAdenocarcinoma of LungAged, 80 and overAsian PeopleCarcinoma, Non-Small-Cell LungCrizotinibFistulaHumansIntestinal PerforationLung NeoplasmsMaleProtein Kinase InhibitorsPyrazolesPyridinesRectumCrizotinibProtein Kinase InhibitorsPyrazolesPyridinesalectinibALK rearrangementcrizotinibintestinal tract perforationnon-small cell lung cancer

Identifiers

PMID29021430
PMCPMC5742395
OpenAlexW2763266634

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.