Evidence map›Paper›PMID 29021398›Full record

ArticleJournal of virology2017

Characterization of the African Swine Fever Virus Decapping Enzyme during Infection.

Ana Quintas, Daniel Pérez-Núñez, Elena G Sánchez, Maria L Nogal, Matthias W Hentze, Alfredo Castelló, Yolanda Revilla

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Hybrid genotype I and II ASFVEmerging microbes & infections · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. African Swine Fever Virus: A Review.Life (Basel, Switzerland) · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Eukaryotic mRNA Decapping Activation.Frontiers in genetics · 2022
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Ana QuintasCentro de Biología Molecular Severo Ochoa, CSIC-UAM, Universidad Autónoma de Madrid, Madrid, Spain.
Daniel Pérez-NúñezCentro de Biología Molecular Severo Ochoa, CSIC-UAM, Universidad Autónoma de Madrid, Madrid, Spain.
Elena G SánchezCentro de Biología Molecular Severo Ochoa, CSIC-UAM, Universidad Autónoma de Madrid, Madrid, Spain.
Maria L NogalCentro de Biología Molecular Severo Ochoa, CSIC-UAM, Universidad Autónoma de Madrid, Madrid, Spain.
Matthias W HentzeEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Alfredo CastellóEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Yolanda RevillaCentro de Biología Molecular Severo Ochoa, CSIC-UAM, Universidad Autónoma de Madrid, Madrid, Spain yrevilla@cbm.csic.es.
Universidad Autónoma de Madrid · ESCentro de Biología Molecular Severo Ochoa · ESEuropean Molecular Biology Laboratory · DEUniversity of Oxford · GB

Funding

Medical Research Council MC_UU_12014/10Medical Research Council MR/L019434/1
6 · The paper itself

Abstract

African swine fever virus (ASFV) infection is characterized by a progressive decrease in cellular protein synthesis with a concomitant increase in viral protein synthesis, though the mechanism by which the virus achieves this is still unknown. Decrease of cellular mRNA is observed during ASFV infection, suggesting that inhibition of cellular proteins is due to an active mRNA degradation process. ASFV carries a gene (Ba71V D250R/Malawi g5R) that encodes a decapping protein (ASFV-DP) that has a Nudix hydrolase motif and decapping activity

Indexed as

African Swine Fever VirusAnimalsChlorocebus aethiopsEndoribonucleasesGene DeletionHost-Pathogen InteractionsNudix HydrolasesProtein BindingPyrophosphatasesRibosomal ProteinsRNA, MessengerSus scrofaVero CellsViral ProteinsEndoribonucleasesmRNA decapping enzymesNudix HydrolasesPyrophosphatasesRibosomal ProteinsRNA, MessengerViral ProteinsAfrican swine fever virusdecappingribosomestranslationvirus-cell interaction

Identifiers

PMID29021398
PMCPMC5709586
OpenAlexW2764087460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.