Evidence map›Paper›PMID 29021384›Full record

ArticleJournal of the American Society of Nephrology : JASN2018

Impaired

Farsad Afshinnia, Thekkelnaycke M Rajendiran, Tanu Soni, Jaeman Byun, Stefanie Wernisch, Kelli M Sas, Jennifer Hawkins, Keith Bellovich, Debbie Gipson, George Michailidis and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 176 citations in OpenAlex.

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  16. New Insights into the Role of Mitochondrial Dysfunction in Diabetic Kidney Disease in the Omics Era.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026
    Review
  17. Article
  18. Article
  19. Article
  20. Article

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Farsad AfshinniaDepartments of Internal Medicine-Nephrology.
Thekkelnaycke M RajendiranBioinformatics and Molecular Phenotyping, Michigan Regional Comprehensive Metabolomics Resource Core, University of Michigan, Ann Arbor, Michigan.
Tanu SoniBioinformatics and Molecular Phenotyping, Michigan Regional Comprehensive Metabolomics Resource Core, University of Michigan, Ann Arbor, Michigan.
Jaeman ByunDepartments of Internal Medicine-Nephrology.
Stefanie WernischDepartments of Internal Medicine-Nephrology.
Kelli M SasDepartments of Internal Medicine-Nephrology.
Jennifer HawkinsDepartments of Internal Medicine-Nephrology.
Keith BellovichDivision of Nephrology, St. Clair Nephrology Research, Detroit, Michigan; and.
Debbie GipsonPediatrics, and.
George MichailidisBioinformatics and Molecular Phenotyping, Michigan Regional Comprehensive Metabolomics Resource Core, University of Michigan, Ann Arbor, Michigan.
Subramaniam PennathurDepartments of Internal Medicine-Nephrology, spennath@umich.edu.
Michigan Kidney Translational Core CPROBE Investigator Group
University of Michigan–Ann Arbor · USPediatrics and Genetics · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Martin G Myers · 2013 to 2026
$24.3M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Joyce Lee · 2010 to 2026
$20.3M
Integrated Systems Biology Approach to Diabetic Microvascular ComplicationsR24DK082841 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ABCOUWER, STEVEN F, BROSIUS, FRANK C · 2008 to 2020
$13.1M
University of Michigan O'Brien Kidney Translational Core CenterP30DK081943 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PENNATHUR, SUBRAMANIAM · 2008 to 2022
$12.9M
Statistics and Bioinformatics Core - WangU24DK097153 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BURANT, CHARLES F · 2012 to 2017
$10.1M
Prognostic Biomarkers in Chronic Kidney DiseaseK08DK106523 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI AFSHINNIA, FARSAD · 2015 to 2019
$789k
NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR002240NIDDK NIH HHS K08 DK106523NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK081943NIDDK NIH HHS P30 DK089503NIDDK NIH HHS R24 DK082841NIDDK NIH HHS U24 DK097153
6 · The paper itself

Abstract

Studies of lipids in CKD, including ESRD, have been limited to measures of conventional lipid profiles. We aimed to systematically identify 17 different lipid classes and associate the abundance thereof with alterations in acylcarnitines, a metric of

Indexed as

Lipid MetabolismOxidation-ReductionAdultAgedAged, 80 and overCarnitineFatty AcidsFemaleHumansKidney Failure, ChronicMaleMiddle AgedSeverity of Illness IndexCarnitineFatty AcidsAcylcarnitineschronic kidney diseasecomplex lipidsFree fatty acidslipids

Identifiers

PMID29021384
PMCPMC5748913
OpenAlexW2764067490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.