Evidence map›Paper›PMID 29021345›Full record

ArticleMolecular biology of the cell2017

Direct evidence of amyloid precursor-like protein 1

Valentin Dunsing, Magnus Mayer, Filip Liebsch, Gerhard Multhaup, Salvatore Chiantia

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Valentin DunsingInstitute of Biochemistry and Biology, University of Potsdam, 14476 Potsdam, Germany.
Magnus MayerInstitute of Chemistry and Biochemistry, Free University of Berlin, 14195 Berlin, Germany.
Filip LiebschDepartment of Pharmacology and Therapeutics/Integrated Program in Neuroscience, McGill University, Montreal, QC H3G 1Y63, Canada.
Gerhard MulthaupDepartment of Pharmacology and Therapeutics/Integrated Program in Neuroscience, McGill University, Montreal, QC H3G 1Y63, Canada.
Salvatore ChiantiaInstitute of Biochemistry and Biology, University of Potsdam, 14476 Potsdam, Germany chiantia@gmail.com.
McGill University · CAUniversity of Potsdam · DEFreie Universität Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The amyloid precursor-like protein 1 (APLP1) is a type I transmembrane protein that plays a role in synaptic adhesion and synaptogenesis. Past investigations indicated that APLP1 is involved in the formation of protein-protein complexes that bridge the junctions between neighboring cells. Nevertheless, APLP1-APLP1

Indexed as

Amyloid beta-Protein PrecursorCell AdhesionCell CommunicationHEK293 CellsHumansNeuronsOptical ImagingProtein BindingSpectrometry, FluorescenceTrans-ActivatorsZincAmyloid beta-Protein PrecursorAPLP1 protein, humanTrans-ActivatorsZinc

Identifiers

PMID29021345
PMCPMC5706989
OpenAlexW2764271470

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.